You are what you eat: dietary salt intake and renin-angiotensin blockade in diabetic nephropathy.

You are what you eat: dietary salt intake and renin-angiotensin blockade in diabetic nephropathy.
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DOI:
10.1038/ki.2012.148
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发表时间:
2012-08
影响因子:
19.6
通讯作者:
--
中科院分区:
医学1区
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--
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Interactions between sodium intake, the renin angiotensin system and renal and cardiovascular outcomes are incompletely understood. Lambers Heerspink et al's analysis shows that angiotensin receptor blockade (ARB) improves diabetic nephropathy and cardiovascular disease more when dietary sodium intake is low and suggests possible harm when sodium intake is high. These findings highlight dietary salt as a modifiable cardiovascular and renal risk factor and emphasize the need for need for detailed mechanistic studies.
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