The quality of life in women with cervical cancer and precancerous lesions of Han and ethnic minorities in Southwest China.
The quality of life in women with cervical cancer and precancerous lesions of Han and ethnic minorities in Southwest China.
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西南地区汉族及少数民族宫颈癌及癌前病变女性生存质量分析
DOI：
10.1186/s12885-021-08856-8
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发表时间：
2021-10-16
期刊：
影响因子：
3.8
通讯作者：
Li Z
中科院分区：
文献类型：
--
作者：
Zhao M;Pu X;Yan YJ;Zhang S;Long X;Luo L;Li Z
研究背景宫颈癌及癌前病变患者诊断早、生存期长，了解其健康相关生活质量，对于制定更好的癌症相关政策、合理分配有限资源具有重要意义。我们在昆明医科大学第三附属医院进行了一项横断面研究，以评估目标人群的健康相关生活质量。由于云南民族的特点，我们的研究人群包括汉族和少数民族。方法采用横断面研究，于2019年1月至2020年12月，选择300例经病理学初步诊断为宫颈癌和宫颈上皮内瘤样病变（CIN）的患者。结果汉族和少数民族患者的生活质量具有较好的可比性。汉族和少数民族的EQ-5D VAS评分差异有统计学意义（平均值分别为85.42和81.01;P<0.05）。两组EQ-5D效用评分略有差异，但无统计学意义（平均值0.959 vs. 0.932;P>0.05）。影响宫颈癌及癌前病变妇女健康相关生活质量的因素有：民族、经济困难、绝经状况和参加全国宫颈癌普查计划（CNCCSP）。此外，我们还发现在CNCCSP和人乳头瘤病毒疫苗的认知度低，以及在全国筛查programmes.ConclusionThe研究结果暗示，HRQoL的差异汉族和少数民族之间确实存在宫颈癌和癌前病变。卫生服务提供者和卫生相关部门需要投入更多的卫生和财政资源，以扩大筛查项目的认识和参与。应在欠发达的少数民族地区做出更多努力，以确保卫生资源和干预措施的可及性。为了减轻疾病造成的经济困难，应该建议对有或没有雇员保险的人实行更平等的保险报销。
BackgroundAs patients with cervical cancer and precancerous lesions can be diagnosed at early stage and live longer, it is imperative to understand their health-related quality of life so that better cancer-related policies could be promoted and reasonable distribution of limited resources could be implemented. We conducted a cross-sectional study in the Third Affiliated Hospital of Kunming Medical University to assess the health-related quality of life in our targeted population. Due to the characteristics of Yunnan nationality, our study population includes both Han people and ethnic minorities.MethodsA cross-sectional study was conducted from January 2019 to December 2020, and 300 patients were selected, who were initially diagnosed with cervical cancer and cervical intraepithelial neoplasia (CIN) pathologically. EQ-5D questionnaire was used to evaluate their quality of life.ResultsPatients in Han and ethnic minorities showed good comparability. EQ-5D VAS score was statistically significant between Han and ethnic minorities (mean, 85.42 vs. 81.01;P<0.05). EQ-5D utility score was slightly different but without statistical significance between the two groups (mean, 0.959 vs. 0.932;P>0.05). Nationality, economic trouble, menopause status and participation of China National Cervical Cancer Screening Program (CNCCSP) are influencing factors of HRQoL among women with cervical cancer and precancerous lesions. Besides, we also found low awareness in the CNCCSP and human papilloma virus vaccine, as well as low participation in the national screening program.ConclusionThe results of our study imply that the difference of HRQoL does exist between Han people and ethnic minorities with cervical cancer and precancerous lesions. Health providers and health-related departments need to invest more health and financial resources to expand the awareness and participation of the screening project. More efforts should be made in underdeveloped minority areas to assure the accessibility of health resources and interventions. To mitigate economic trouble caused by the diseases, more equal insurance reimbursement should be suggested and implemented in people with or without employee insurance.
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影响因子：
6.9
作者：
Harper, A;Power, M
通讯作者：
Power, M
影响因子：
3.5
作者：
Li, Chia-Chun;Chang, Ting-Chang;Chen, Lynn
通讯作者：
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影响因子：
9.3
作者：
ACTION Study Group
通讯作者：
ACTION Study Group
DOI：
10.1016/j.ijrobp.2008.06.1905
发表时间：
2009-04-01
影响因子：
7
作者：
Korfage, Ida J.;Essink-Bot, Marie-Louise;van Ballegooijen, Marjolein
通讯作者：
van Ballegooijen, Marjolein
影响因子：
5.8
作者：
Wang, Baohua;He, Minfu;Wang, Linhong
通讯作者：
Wang, Linhong