The effects of an imperfect vaccine on cholera control

The effects of an imperfect vaccine on cholera control
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不完善的疫苗对霍乱控制的影响

DOI:
10.4236/abb.2013.43052
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发表时间:
2013-03
期刊:
Advances in Bioscience and Biotechnology
影响因子:
--
通讯作者:
Guohua Song
Guohua Song
中科院分区:
其他
文献类型:
--
作者:
Jingan Cui;Zhanmin Wu;Guohua Song

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在本文中,我们考虑了疫苗接种不完善的 SVIR-B 霍乱模型。通过分析相应的特征方程,建立了无病平衡和地方病平衡的局部渐近稳定性。我们计算一定的阈值,称为基本再生数Rv。如果房车社区。通过比较论证,证明如果Rv > 1,则唯一的地方性平衡是局部渐近稳定的。我们对 Rv 对参数进行敏感性分析,以确定它们对疾病控制的相对重要性,并表明不完善的疫苗始终有利于减少社区内的疾病传播。
In this paper, we consider a SVIR-B cholera model with imperfect vaccination. By analyzing the corresponding characteristic equations, the local asymptotically stability of a disease-free equilibrium and an endemic equilibrium is established. We calculate the certain threshold known as the basic reproduction number Rv. If Rv the community. By comparison arguments, it is proved that if Rv > 1, the unique endemic equilibrium is local asymptotically stable. We perform sensitivity analysis of Rv on the parameters in order to determine their relative importance to disease control and show that an imperfect vaccine is always beneficial in reducing disease spread within the community.
高感染力:V.霍乱引起流行病的能力的关键要素?
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