Phase transitions during fruiting body formation in Myxococcus xanthus
Phase transitions during fruiting body formation in Myxococcus xanthus
复制标题
黄色粘球菌子实体形成过程中的相变
DOI：
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
J. Shaevitz
中科院分区：
文献类型：
--
作者：
S. Thutupalli;Mingzhai Sun;F. Bunyak;K. Palaniappan;J. Shaevitz
集体迁徙群体的形成以各种方式使种群中的个体受益，例如对扰动的超敏感性，集体摄食模式以及免受环境压力的保护。虽然一些集体组织使用单一的组织原则，但其他集体组织可以通过修改个人层面的交互规则来动态地改变群体的行为。表面生长的细菌粘液球菌形成动态的集体群体，既以猎物为食，又在饥饿时聚集。后一种行为被称为子实体的形成，涉及一系列复杂的、协调的密度变化，最终导致由数十万个细胞和孢子组成的三维聚集体。这个多步骤的发育过程很可能涉及几种不同的单细胞行为，因为种群从松散的二维薄片凝结成三维丘。在这里，我们使用高分辨率显微镜和计算机视觉软件来时空跟踪数千个个体在子实体形成初期的运动。我们发现细胞接触介导的对齐和内部
The formation of a collectively moving group benets individuals within a population in a variety of ways such as ultra-sensitivity to perturbation, collective modes of feeding, and protection from environmental stress. While some collective groups use a single organizing principle, others can dynamically shift the behavior of the group by modifying the interaction rules at the individual level. The surfacedwelling bacterium Myxococcus xanthus forms dynamic collective groups both to feed on prey and to aggregate during times of starvation. The latter behavior, termed fruiting-body formation, involves a complex, coordinated series of density changes that ultimately lead to three-dimensional aggregates comprising hundreds of thousands of cells and spores. This multi-step developmental process most likely involves several dierent single-celled behaviors as the population condenses from a loose, two-dimensional sheet to a three-dimensional mound. Here, we use highresolution microscopy and computer vision software to spatiotemporally track the motion of thousands of individuals during the initial stages of fruiting body formation. We nd that a combination of cell-contact-mediated alignment and internal
DOI：
10.1073/pnas.82.24.8767
发表时间：
1985-12-01
影响因子：
11.1
作者：
BLACKHART, BD;ZUSMAN, DR
通讯作者：
ZUSMAN, DR
影响因子：
44.1
作者：
Marchetti, M. C.;Joanny, J. F.;Simha, R. Aditi
通讯作者：
Simha, R. Aditi