Sleep Dysfunction in COVID-19 Patients: Prevalence, Risk Factors, Mechanisms, and Management.
Sleep Dysfunction in COVID-19 Patients: Prevalence, Risk Factors, Mechanisms, and Management.
复制标题
DOI：
10.3390/jpm11111203
复制
发表时间：
2021-11-14
影响因子：
--
通讯作者：
Pappa S
中科院分区：
文献类型：
--
作者：
Pataka A;Kotoulas S;Sakka E;Katsaounou P;Pappa S
在 COVID-19 大流行期间，确定睡眠功能障碍和心理困扰的患病率、识别诱发因素和保护因素以及探索有效的管理策略仍然是一个重要的优先事项。迄今为止的证据表明，相当一部分 COVID-19 患者经历了严重的睡眠障碍（估计高达 50-75%）以及抑郁、焦虑和创伤性应激等心理困扰。住院时间、先前存在的心理健康问题、淋巴细胞绝对计数较低以及中性粒细胞与淋巴细胞比率增加都与感染和住院患者睡眠功能障碍的风险增加有关。此外，在这篇综述中，我们讨论了与 COVID-19 相关的睡眠剥夺、病毒感染易感性和社会心理健康之间的联系，并总结了有关感染者睡眠呼吸暂停的存在和作用的现有证据。最后，我们强调适当干预措施的重要性，以预防和管理睡眠功能障碍并避免长期的身体和心理影响。未来的研究应旨在提供高质量的信息，包括高风险、服务不足或难以接触的人群以及所应用干预措施的长期后果和有效性。
During the COVID-19 pandemic, the need to establish the prevalence of sleep dysfunction and psychological distress, identify predisposing and protective factors, and explore effective management strategies remains an important priority. Evidence to date suggests that a considerable proportion of COVID-19 patients experience significant sleep disturbances (estimated to afflict up to 50–75%) as well as psychological distress such as depression, anxiety, and traumatic stress. Duration of hospitalization, pre-existing mental health concerns, lower absolute lymphocyte count, and increased neutrophil-to-lymphocyte ratio have been all associated with a greater risk of sleep dysfunction in infected and hospitalized patients. Furthermore, in this review, we discuss the link between sleep deprivation, susceptibility to viral infections, and psychosocial wellbeing in relevance to COVID-19 and summarize the existing evidence regarding the presence and role of sleep apnea in infected individuals. Finally, we highlight the importance of suitable interventions in order to prevent and manage sleep dysfunction and avoid long-term physical and psychological implications. Future research should aim to provide high-quality information including in high risk, underserved, or difficult to reach populations and on the long-term consequences and effectiveness of applied interventions.
登录
查看更多内容
影响因子：
24.8
作者：
Irwin MR
通讯作者：
Irwin MR
影响因子：
2.8
作者：
da Silva, Flavia Rodrigues;Guerreiro, Renato de Carvalho;de Mello, Marco Tulio
通讯作者：
de Mello, Marco Tulio
影响因子：
9.9
作者：
Frontera, Jennifer A.;Sabadia, Sakinah;Galetta, Steven
通讯作者：
Galetta, Steven
影响因子：
4.8
作者：
Bastien, Celyne H.;Vallieres, Annie;Morin, Charles M.
通讯作者：
Morin, Charles M.
影响因子：
4.3
作者：
Edinger, Jack D.;Arnedt, J. Todd;Martin, Jennifer L.
通讯作者：
Martin, Jennifer L.