Sensitization to the psychosis-inducing effects of cocaine compared with measures of cocaine craving and cue reactivity.

Sensitization to the psychosis-inducing effects of cocaine compared with measures of cocaine craving and cue reactivity.
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与可卡因渴望和提示反应性的测量相比,对可卡因诱发精神病的作用的敏感性。

DOI:
10.1080/10550490490460175
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发表时间:
2004
期刊:
The American journal on addictions / American Academy of Psychiatrists in Alcoholism and Addictions.
影响因子:
--
通讯作者:
Angrist,Burt
Angrist,Burt
中科院分区:
--
文献类型:
--
作者:
Reid,MalcolmS;Ciplet,Debra;O'Leary,Siobhan;Branchey,Marc;Buydens-Branchey,Laure;Angrist,Burt

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以前的一项研究表明,对可卡因的精神病诱导作用敏感可能是可卡因成瘾易复发的标志。在本报告中,对参与自然发生和线索诱导的可卡因渴望研究的可卡因依赖受试者进行了访谈,了解可卡因诱导的精神病的既往经历,以及这种影响变得更频繁或更严重或在较低累积剂量下发生的程度。可卡因引起的精神病的敏感性呈负相关,基线措施的药物依赖的严重程度和指数的可卡因渴望在过去的24小时,但没有可卡因线索反应的措施。(Am J Addict 2004;13:305-315)
A previous study has suggested that sensitization to the psychosis-inducing effects of cocaine may be a marker of vulnerability to relapse in cocaine addiction. In this report, cocaine-dependent subjects participating in a study on naturally occurring and cue-induced cocaine craving were interviewed about prior experience of cocaine-induced psychosis and the degree to which this effect had become more frequent or severe or had occurred at lower cumulative doses. Sensitization to cocaine-induced psychosis was negatively correlated with baseline measures of drug dependence severity and indices of cocaine craving over the preceding 24 hours but not with measures of cocaine cue reactivity. (Am J Addict 2004;13:305–315)
对各种滥用药物的渴望和戒断症状
DOI: --
发表时间: 1998
期刊:
影响因子: --
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