Direct evidence of the relationship between brain metastatic adenocarcinoma and white matter fibers: A fiber dissection and diffusion tensor imaging tractography study
Direct evidence of the relationship between brain metastatic adenocarcinoma and white matter fibers: A fiber dissection and diffusion tensor imaging tractography study
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脑转移性腺癌与白质纤维之间关系的直接证据：纤维解剖和扩散张量成像纤维束成像研究
DOI：
10.1016/j.jocn.2020.05.043
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发表时间：
2020
影响因子：
2
通讯作者：
Nakada Mitsutoshi
中科院分区：
文献类型：
--
作者：
Liu Xiaoliang;Kinoshita Masashi;Shinohara Harumichi;Hori Osamu;Ozaki Noriyuki;Hatta Toshihisa;Honma Satoru;Nakada Mitsutoshi
众所周知，脑转移瘤在磁共振成像中通常边界清楚。然而，关于白质纤维在肿瘤周围的轨迹，尤其是使用纤维剥离技术，人们知之甚少。在这里，我们重点研究了白质纤维和肿瘤之间的解剖相互作用，使用纤维解剖的死后脑转移瘤，并与弥散张量成像(DTI)纤维束成像的结果进行比较。对1例Broca区转移性腺癌的人大脑半球进行了解剖，采用Klingler方法进行纤维解剖。为了比较体外和活体结果，对15例转移性腺癌患者的附加脑进行了DTI成像重建，其体积与用于纤维剥离的脑腺癌相当。比较两种技术对肿瘤周围白质束形态的影响。在纤维剥离技术中，可以剥离上纵束、弓形束和额斜束，并将白质束弯曲和回缩以避免肿瘤的发生。在所有分析的病例中，肿瘤周围的白质纤维或流线避开了病变。使用纤维解剖技术，这是第一个直接证据来阐明受脑转移影响的白质纤维的解剖。这表明脑转移性腺癌是一种轴内肿瘤，具有轴外白质结构。
It is commonly known that brain metastases usually have clear boundaries in magnetic resonance imaging. However, little is known regarding the trajectory of white matter fibers around the tumors, especially using the fiber dissection technique. Here, we focused on the anatomical interaction between white matter fibers and the tumor, using the fiber dissection in a postmortem brain with metastatic tumor and compared the findings with those of diffusion tensor imaging (DTI) tractography. One postmortem human brain hemisphere with metastatic adenocarcinoma in the Broca’s area was dissected using fiber dissection following the Klingler’s method. In order to compare thein vitroandin vivoresults, additional brains from 15 patients with metastatic adenocarcinomas, the volumes of which were comparable to that of the adenocarcinoma in the brain used for fiber dissection, were analyzed using DTI tractographic reconstruction. Morphological findings of white matter bundles running around the tumor were compared between the two techniques. In the fiber dissection technique, the superior longitudinal fascicle, arcuate fascicle, and frontal aslant tract could be dissected, and the white matter bundles were curved and retracted to avoid the tumor. In all the cases analyzed, white matter fibers or streamlines surrounding the tumor avoided the lesion. Using the fiber dissection technique, this is the first direct evidence to elucidate the anatomy of white matter fibers affected by a metastatic brain. This suggests that brain metastatic adenocarcinoma is an intra-axial neoplasm with extra-axial white matter structures.
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影响因子：
3.7
作者：
Lehéricy, S;Ducros, M;Kim, DS
通讯作者：
Kim, DS
影响因子：
4.8
作者：
Ugur T??re;M. Gazi Ya??argil;T. G. Pait
通讯作者：
T. G. Pait
体内 MR 测定水扩散系数和扩散各向异性：与大脑半球胶质瘤结构改变的相关性。
DOI：
--
发表时间：
1995
期刊：
AJNR. American journal of neuroradiology
影响因子：
--
作者：
J. Brunberg;T. Chenevert;P. Mckeever;D. Ross;L. Junck;K. Muraszko;R. Dauser;J. Pipe;A. T. Betley
通讯作者：
A. T. Betley
皮质脊髓束的肿瘤受累：弥散磁共振纤维束成像与术中相关性。
影响因子：
4.1
作者：
A. Holodny;T. Schwartz;M. Ollenschleger;W. C. Liu;M. Schulder
通讯作者：
M. Schulder
功能皮质和皮质下白质位于神经胶质瘤内。
影响因子：
4.8
作者：
Skirboll,SS;Ojemann,GA;Berger,MS;Lettich,E;Winn,HR
通讯作者：
Winn,HR