Correlation of dried blood spots and plasma for quantification of Immunoglobulin (IgG) against Receptor binding domain and full length spike protein of SARS-CoV-2.
Correlation of dried blood spots and plasma for quantification of Immunoglobulin (IgG) against Receptor binding domain and full length spike protein of SARS-CoV-2.
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DOI:
10.1016/j.jviromet.2021.114394
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发表时间:
2022-03
影响因子:
3.1
通讯作者:
Madhi SA
中科院分区:
文献类型:
--
作者:
Kwatra G;Nunes M;Dhar N;Baillie V;Serafin N;Jones S;Madhi SA
We compared plasma and dried blood spots for detection of SARS-CoV-2 IgG antibodies. There was a good correlation between IgG values measured by both sampling methods, r = 0.935 and 0.965 for Receptor Binding Domain and full-length spike protein of SARS-CoV-2. Bland-Altman assessment showed good agreement between two sampling methods. Dried blood spots is a more pragmatic method for collecting samples for sero-epidemiological surveys of SARS-CoV-2 infection.
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