SpatialDE: identification of spatially variable genes.
SpatialDE: identification of spatially variable genes.
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DOI:
10.1038/nmeth.4636
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发表时间:
2018-05
期刊:
影响因子:
48
通讯作者:
Stegle O
中科院分区:
文献类型:
--
作者:
Svensson V;Teichmann SA;Stegle O
Technological advances have made it possible to measure spatially resolved gene expression at high throughput. However, methods to analyze these data are not established. Here, we develop SpatialDE, a statistical test to identify genes with spatial patterns of expression variation from multiplexed imaging or spatial RNA sequencing data. SpatialDE also implements “automatic expression histology”, a spatial gene clustering approach that enables expression-based tissue histology.
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影响因子:
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