Electrochemical Oscillatory Baffled Reactors Fabricated with Additive Manufacturing for Efficient Continuous-Flow Oxidations.
Electrochemical Oscillatory Baffled Reactors Fabricated with Additive Manufacturing for Efficient Continuous-Flow Oxidations.
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DOI：
10.1021/acssuschemeng.1c06799
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发表时间：
2022-02-21
影响因子：
8.4
通讯作者：
Sans V
中科院分区：
文献类型：
--
作者：
Alvarez E;Romero-Fernandez M;Iglesias D;Martinez-Cuenca R;Okafor O;Delorme A;Lozano P;Goodridge R;Paradisi F;Walsh DA;Sans V
电化学连续流反应器为强化和可持续的化学合成提供了很好的机会。在这里，我们介绍了电化学连续流振荡折流板反应器(ECOBRs)的一种新应用，它将先进的混合特性与电化学转换相结合，使电极之间在毫米级连续流动下能够有效地进行电化学氧化。不同的添加剂制造技术已经被用来快速制造反应堆。NADH的电化学氧化是生物催化转化中酶再生的关键，是一种非常敏感的底物，已被用作基准反应。振荡条件改善了整体混合，促进了试剂与电极的接触。在振荡条件下，ECOBR在NADH的电化学氧化中表现出更好的性能，这归因于与振荡相关的更好的传质。连续流动的电化学隔板反应器提高了混合效率，从而改善了传质。证明了NADH的电化学氧化作用。
Electrochemical continuous-flow reactors offer a great opportunity for enhanced and sustainable chemical syntheses. Here, we present a novel application of electrochemical continuous-flow oscillatory baffled reactors (ECOBRs) that combines advanced mixing features with electrochemical transformations to enable efficient electrochemical oxidations under continuous flow at a millimeter distance between electrodes. Different additive manufacturing techniques have been employed to rapidly fabricate reactors. The electrochemical oxidation of NADH, a very sensitive substrate key for the regeneration of enzymes in biocatalytic transformations, has been employed as a benchmark reaction. The oscillatory conditions improved bulk mixing, facilitating the contact of reagents to electrodes. Under oscillatory conditions, the ECOBR demonstrated improved performance in the electrochemical oxidation of NADH, which is attributed to improved mass transfer associated with the oscillatory regime. Continuous-flow electrochemical baffled reactors enhance mixing efficiency that improves mass transfer. The electrochemical oxidation of NADH has been demonstrated.
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