Evidence that perinatal ovarian hormones promote women's sexual attraction to men.

Evidence that perinatal ovarian hormones promote women's sexual attraction to men.
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有证据表明,围产期卵巢激素会促进女性对男性的性吸引力。

DOI:
10.1016/j.psyneuen.2021.105431
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发表时间:
2021-09-27
影响因子:
3.7
通讯作者:
Puts DA
Puts DA
中科院分区:
医学2区
文献类型:
--
作者:
Shirazi TN;Self H;Dawood K;Welling LLM;Cárdenas R;Rosenfield KA;Bailey JM;Balasubramanian R;Delaney A;Breedlove SM;Puts DA

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卵巢雌激素可能会影响人类大脑和行为的发育,但很少有机会测试这种可能性。孤立性促性腺激素释放激素缺乏症(IGD)是一种罕见的内分泌疾病,可以为雌激素在组织性别分化表型中的作用提供证据:与典型的发育不同,IGD患者的发育特征是妊娠前三个月后性腺激素分泌减少或缺乏。由于外生殖器在妊娠早期发育,IGD患者的外观与性腺性别是一致的。因此,我们通过比较IGD患者(n=97)和对照组(n=1670)来研究性激素对性取向的影响。患有IGD的女性报告称,与典型的发育中女性相比,女性对男性的吸引力较低。相比之下,IGD和典型发育中的男性之间没有明显的性别差异。怀孕前三个月后的卵巢激素似乎会影响女性--性取向的典型维度。
Ovarian estrogens may influence the development of the human brain and behavior, but there are few opportunities to test this possibility. Isolated GnRH deficiency (IGD) is a rare endocrine disorder that could provide evidence for the role of estrogens in organizing sexually differentiated phenotypes: Unlike typical development, development in individuals with IGD is characterized by low or absent gonadal hormone production after the first trimester of gestation. Because external genitalia develop in the first trimester, external appearance is nevertheless concordant with gonadal sex in people with IGD. We therefore investigated the effects of gonadal hormones on sexual orientation by comparing participants with IGD (n = 97) to controls (n = 1670). Women with IGD reported lower male-attraction compared with typically developing women. In contrast, no consistent sexuality differences between IGD and typically developing men were evident. Ovarian hormones after the first trimester appear to influence female-typical dimensions of sexual orientation.
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