Epidemiological Variations in the Global Burden of Psoriasis, an Analysis With Trends From 1990 to 2017.
Epidemiological Variations in the Global Burden of Psoriasis, an Analysis With Trends From 1990 to 2017.
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全球银屑病负担的流行病学变化，1990 年至 2017 年趋势分析。
DOI：
10.3389/fmed.2021.585634
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发表时间：
2021
影响因子：
3.9
通讯作者：
Lu J
中科院分区：
文献类型：
--
作者：
Peng C;Xu X;Chen W;Li X;Yi X;Ding Y;Yu N;Lu J
背景：虽然已有许多流行病学研究，但在全球范围内关注银屑病健康负担的研究仍然缺乏。银屑病全球健康负担的趋势和变化通过时间，年龄，性别，地理位置和社会经济地位进行评估，使用全球疾病负担研究的残疾调整生命年（DADs）。研究方法：银屑病的健康负担是由DALTS评估的，它将残疾损失年数（发病率组成部分）与寿命损失年数（死亡率组成部分）结合起来。全球和国家的残疾人数量、粗残疾人比率和年龄标准化残疾人比率均来自GBD 2017研究数据库。相应的人类发展指数是从联合国开发计划署收集的。结果：从1990年到2017年，银屑病患者人数和粗患病率分别增加了73%和22%。相比之下，年龄标准化的残疾人比率略有上升。65-69岁年龄范围内的患者承担更显著的银屑病负担。在过去的27年里，男性和女性的银屑病负担都呈增加趋势，女性的银屑病负担比男性更严重。银屑病的健康负担在地理上基本上是不平等的，基尼系数为0.27。集中指数表明银屑病负担的社会经济相关不平等，值为0.22，占各国方差的48.64%（R2 = 0.4864，p < 0.001）。在过去的27年中，银屑病负担分布的国家间不平等继续下降。银屑病负担的基尼系数从1990年的0.280下降到2017年的0.265。集中度指数显示了相同的趋势，20世纪90年代为0.236，2017年为0.223。结论：在过去的几十年里，银屑病的全球健康进展以及不平等。虽然银屑病负担的不平等在过去27年中有所改善，但在年龄，性别，地理位置以及社会经济地位方面仍然存在差异。这项研究的结果突出了银屑病的全球重要性，对于全球范围内银屑病服务的政策规划非常重要。
Background: Although there have been many epidemiological studies, research focusing on psoriasis' health burden on a global scale is still lacking. Trends and variations in the global health burden of psoriasis are evaluated by time, age, gender, geographical location, and socioeconomic status, using disability-adjusted life years (DALYs) from the Global Burden of Disease Study. Methods: The health burden of psoriasis was evaluated by DALYs, which combined years lost to disability (a morbidity component) with years of life lost (a mortality component). The global and national DALYs number, crude DALYs rate, and age-standardized DALYs rate were obtained from the GBD 2017 study database. The corresponding human development index (HDI) was collected from the United Nations Development Programme. Results: From 1990 to 2017, the DALYs number and crude DALYs rate due to psoriasis increased by 73 and 22%, respectively. In comparison, the age-standardized DALYs rate showed a slight increase. Patients in the age range of 65–69 years bear a more significant psoriasis burden. Both males and females showed an increasing trend in burden caused by psoriasis over the past 27 years, with females bearing a more significant psoriasis burden than males. The health burden of psoriasis was substantially unequal in geography with a Gini coefficient of 0.27. The concentration indexes indicated a socioeconomic associated inequality in psoriasis burden with values of 0.22, accounting for 48.64% variance across countries (R2 = 0.4864, p < 0.001). Between-nation inequality in the distribution of psoriasis burden continued to decline throughout the past 27 years. Gini coefficients of psoriasis burden decreased from 0.280 in 1990 to 0.265 in 2017. The concentration indexes indicated the same trend with 0.236 in the 1990s and 0.223 in 2017. Conclusions: Global health progress in psoriasis together with inequality in the past few decades. Although the inequality of psoriasis burden has shown some improvement during the past 27 years, disparities still exist in age, gender, geographical location, as well as socioeconomic status. The findings of this study highlight the global importance of psoriasis and is important in policy planning for psoriasis services on a global scale.
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DOI：
10.1016/j.jaad.2015.02.1099
发表时间：
2015-06-01
影响因子：
13.8
作者：
Vanderpuye-Orgle, Jacqueline;Zhao, Yang;Lebwohl, Mark
通讯作者：
Lebwohl, Mark
影响因子：
3.7
作者：
Armstrong AW;Schupp C;Wu J;Bebo B
通讯作者：
Bebo B
影响因子：
3.5
作者：
Bleichrodt, Han;van Doorslaer, Eddy
通讯作者：
van Doorslaer, Eddy
影响因子：
4.1
作者：
Napolitano, M.;Mastroeni, S.;Abeni, D.
通讯作者：
Abeni, D.
影响因子：
168.9
作者：
Swinburn, Boyd A.;Sacks, Gary;Gortmaker, Steven L.
通讯作者：
Gortmaker, Steven L.