The genetics-BIDS extension: Easing the search for genetic data associated with human brain imaging.

The genetics-BIDS extension: Easing the search for genetic data associated with human brain imaging.
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DOI:
10.1093/gigascience/giaa104
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发表时间:
2020-10-17
期刊:
影响因子:
9.2
通讯作者:
Pernet CR
Pernet CR
中科院分区:
生物学2区
文献类型:
--
作者:
Moreau CA;Jean-Louis M;Blair R;Markiewicz CJ;Turner JA;Calhoun VD;Nichols TE;Pernet CR

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元数据使数据库可搜索。如果没有它们,研究人员将很难找到具有他们感兴趣的特征的数据。脑成像遗传学是两个学科的交叉点,每个学科都有专用的字典和本体,便于数据搜索和分析。在这里,我们提出了遗传学脑成像数据结构扩展,包括人脑成像数据的元数据文件,它们被链接到,并简要地描述了与它们相关的基因组和转录组数据,这可能是在不同的数据库。这种扩展将有助于识别与宏观尺度成像库相关联的微观尺度分子特征,从而促进跨研究的数据聚合。
Metadata are what makes databases searchable. Without them, researchers would have difficulty finding data with features they are interested in. Brain imaging genetics is at the intersection of two disciplines, each with dedicated dictionaries and ontologies facilitating data search and analysis. Here, we present the genetics Brain Imaging Data Structure extension, consisting of metadata files for human brain imaging data to which they are linked, and describe succinctly the genomic and transcriptomic data associated with them, which may be in different databases. This extension will facilitate identifying micro-scale molecular features that are linked to macro-scale imaging repositories, facilitating data aggregation across studies.
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