Recent Advances in Structural Studies of Single-Stranded RNA Bacteriophages.
Recent Advances in Structural Studies of Single-Stranded RNA Bacteriophages.
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DOI：
10.3390/v15101985
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发表时间：
2023-09-23
期刊：
影响因子：
--
通讯作者：
Zhang J
中科院分区：
文献类型：
--
作者：
Thongchol J;Lill Z;Hoover Z;Zhang J
正义单链RNA噬菌体（Positive-sense single-stranded RNA bacteriophage，ssRNA）是在60年前首次分离出来的。从那时起，人们对这些ssRNA酶进行了广泛的研究，特别是那些感染E.杆菌由于通常编码四种必需蛋白质的通常为3- 4kb的小基因组，ssRNA噬菌体采用直接的感染循环，包括宿主吸附、基因组进入、基因组复制、噬菌体组装和宿主裂解。宏基因组学和转录组学的最新进展已经从ssRNA噬菌体中识别出约65，000个序列，扩大了我们对其流行率和潜在宿主的了解。这篇综述文章阐明了对ssRNA的重要研究，重点是它们的结构方面，提供了对它们感染周期各个阶段的见解。
Positive-sense single-stranded RNA (ssRNA) bacteriophages (phages) were first isolated six decades ago. Since then, extensive research has been conducted on these ssRNA phages, particularly those infecting E. coli. With small genomes of typically 3–4 kb that usually encode four essential proteins, ssRNA phages employ a straightforward infectious cycle involving host adsorption, genome entry, genome replication, phage assembly, and host lysis. Recent advancements in metagenomics and transcriptomics have led to the identification of ~65,000 sequences from ssRNA phages, expanding our understanding of their prevalence and potential hosts. This review article illuminates significant investigations into ssRNA phages, with a focal point on their structural aspects, providing insights into the various stages of their infectious cycle.
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DOI：
10.1073/pnas.1707102114
发表时间：
2017-10-01
影响因子：
11.1
作者：
Cui, Zhicheng;Gorzelnik, Karl V.;Zhang, Junjie
通讯作者：
Zhang, Junjie
影响因子：
5.6
作者：
Tomita K
通讯作者：
Tomita K
宏基因组时代的单基因裂解。
影响因子：
5.4
作者：
Chamakura KR;Young R
通讯作者：
Young R
影响因子：
3.9
作者：
Callanan J;Stockdale SR;Adriaenssens EM;Kuhn JH;Rumnieks J;Pallen MJ;Shkoporov AN;Draper LA;Ross RP;Hill C
通讯作者：
Hill C
影响因子：
14.8
作者：
Adler, Benjamin A.;Chamakura, Karthik;Carion, Heloise;Krog, Jonathan;Deutschbauer, Adam M.;Young, Ry;Mutalik, Vivek K.;Arkin, Adam P.
通讯作者：
Arkin, Adam P.