IDconverter and IDClight: conversion and annotation of gene and protein IDs.

IDconverter and IDClight: conversion and annotation of gene and protein IDs.
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DOI:
10.1186/1471-2105-8-9
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发表时间:
2007-01-10
期刊:
影响因子:
3
通讯作者:
Díaz-Uriarte R
Díaz-Uriarte R
中科院分区:
生物学4区
文献类型:
--
作者:
Alibés A;Yankilevich P;Cañada A;Díaz-Uriarte R

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参与大量基因、克隆或蛋白质标识符注释的研究人员通常需要对每个标识符进行逐个转换。当研究领域是微阵列实验时,这个数字可能在30,000左右。为了帮助研究人员在克隆、基因、蛋白质和染色体位置之间绘制接入号和标识符,我们设计并开发了IDconverter和IDClight。它们是两个用户友好的、免费提供的web服务器应用程序,还通过将标识符映射到路径、基因本体术语和文献参考来提供额外的功能信息。这两种工具都是面向高通量的,并包括大多数常见基因组数据库的标识符。这些工具已经与其他类似工具进行了比较,表明它们是最快和最新的工具之一。这些工具提供了一种快速和直观的方式来丰富来自高通量实验(如微阵列)的信息。它们对湿实验室研究人员和生物信息学家都很有价值。
Researchers involved in the annotation of large numbers of gene, clone or protein identifiers are usually required to perform a one-by-one conversion for each identifier. When the field of research is one such as microarray experiments, this number may be around 30,000. To help researchers map accession numbers and identifiers among clones, genes, proteins and chromosomal positions, we have designed and developed IDconverter and IDClight. They are two user-friendly, freely available web server applications that also provide additional functional information by mapping the identifiers on to pathways, Gene Ontology terms, and literature references. Both tools are high-throughput oriented and include identifiers for the most common genomic databases. These tools have been compared to other similar tools, showing that they are among the fastest and the most up-to-date. These tools provide a fast and intuitive way of enriching the information coming out of high-throughput experiments like microarrays. They can be valuable both to wet-lab researchers and to bioinformaticians.
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