Motivators, concerns, and barriers to adoption of preexposure prophylaxis for HIV prevention among gay and bisexual men in HIV-serodiscordant male relationships.

Motivators, concerns, and barriers to adoption of preexposure prophylaxis for HIV prevention among gay and bisexual men in HIV-serodiscordant male relationships.
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DOI:
10.1080/09540121.2011.554528
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发表时间:
2011-09
期刊:
影响因子:
1.7
通讯作者:
Leibowitz AA
Leibowitz AA
中科院分区:
医学4区
文献类型:
--
作者:
Brooks RA;Kaplan RL;Lieber E;Landovitz RJ;Lee SJ;Leibowitz AA

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本研究的目的是确定因素,可能会促进或阻碍未来采用暴露前预防(PrEP)的艾滋病毒预防男同性恋和双性恋男子之间的艾滋病毒血清不一致的关系。本定性研究采用半结构化访谈进行了多种族/民族的样本25同性恋和双性恋艾滋病毒血清不一致的男性夫妇(n=50人),从社区环境中招募洛杉矶,加州。一个修改后的扎根理论的方法,以确定有关的主要主题,未来通过的准备预防艾滋病毒的预防。采用的动机包括防止艾滋病毒感染,减少对艾滋病毒传播的关注和恐惧,有机会进行无保护的性行为,以及对PrEP有效性的认可。关注和障碍,通过包括PrEP的成本,短期和长期的副作用,间歇性使用或中断PrEP的不良影响,以及PrEP的可及性。研究结果表明,需要一个精心策划的实施方案沿着教育和咨询干预措施,在传播有效的PrEP代理。
The purpose of this study was to identify factors that may facilitate or impede future adoption of pre-exposure prophylaxis (PrEP) for HIV prevention among gay and bisexual men in HIV-serodiscordant relationships. This qualitative study utilized semi-structured interviews conducted with a multi-racial/ethnic sample of 25 gay and bisexual HIV serodiscordant male couples (n=50 individuals) recruited from community settings in Los Angeles, California. A modified grounded theory approach was employed to identify major themes relating to future adoption of PrEP for HIV prevention. Motivators for adoption included protection against HIV infection, less concern and fear regarding HIV transmission, the opportunity to engage in unprotected sex, and endorsements of PrEP’s effectiveness. Concerns and barriers to adoption included the cost of PrEP, short- and long-term side effects, adverse effects of intermittent use or discontinuing PrEP, and accessibility of PrEP. The findings suggest the need for a carefully planned implementation program along with educational and counseling interventions in the dissemination of an effective PrEP agent.
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