Walking activity in a large cohort of boys with Duchenne muscular dystrophy.
Walking activity in a large cohort of boys with Duchenne muscular dystrophy.
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DOI：
10.1002/mus.27119
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发表时间：
2021-03
期刊：
影响因子：
3.4
通讯作者：
Vandenborne K
中科院分区：
文献类型：
--
作者：
Lott DJ;Taivassalo T;Senesac CR;Willcocks RJ;Harrington AM;Zilke K;Cunkle H;Powers C;Finanger EL;Rooney WD;Tennekoon GI;Vandenborne K
In this study we explored walking activity in a large cohort of boys with Duchenne muscular dystrophy (DMD). Step activity (monitored for 7 days), functional ability, and strength were quantified in ambulatory boys (5-12.9 years of age) with DMD and unaffected boys. Ambulatory status was determined 2 years later. Two to 5 days of activity monitoring predicted weekly step activity (adjusted R2 = 0.80-0.95). Age comparisons revealed significant declines for step activity with increasing age, and relationships were found between step activity with both function and strength (P < .01). Our regression model predicted 36.5% of the variance in step activity. Those who were still ambulatory after 2 years demonstrated baseline step activity nearly double that of those who were no longer walking 2 years later (P < .01). Step activity for DMD is related to and predictive of functional declines, which may be useful for clinical trials.
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影响因子：
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作者：
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通讯作者：
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影响因子：
2.9
作者：
Arpan, Ishu;Forbes, Sean C.;Lott, Donovan J.;Senesac, Claudia R.;Daniels, Michael J.;Triplett, William T.;Deol, Jasjit K.;Sweeney, H. Lee;Walter, Glenn A.;Vandenborne, Krista
通讯作者：
Vandenborne, Krista
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通讯作者：
Peltz, Stuart
DOI：
10.1186/1479-5868-6-31
发表时间：
2009-06-03
影响因子：
8.7
作者：
Hawkins, Marquis S.;Storti, Kristi L.;Kriska, Andrea M.
通讯作者：
Kriska, Andrea M.
影响因子：
1.7
作者：
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通讯作者：
Bell, David