Positional independence of optic nerve head and retinal nerve fiber layer thickness measurements with spectral-domain optical coherence tomography.
Positional independence of optic nerve head and retinal nerve fiber layer thickness measurements with spectral-domain optical coherence tomography.
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DOI：
10.1016/j.ajo.2012.03.049
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发表时间：
2012-10
影响因子：
4.2
通讯作者：
Weinreb, Robert N.
中科院分区：
文献类型：
--
作者：
Mansouri, Kaweh;Liu, John H. K.;Tafreshi, Ali;Medeiros, Felipe A.;Weinreb, Robert N.
目的使用便携式谱域光学相干断层扫描（iVue SD-OCT；Optovue Inc）评估坐位和仰卧位的视神经乳头（ONH）和视网膜神经纤维层（RNFL）厚度测量的可重复性和位置独立性。设计评估诊断技术。方法30名受试者的60只眼睛（10名20-27岁的健康年轻人，10名20岁以上的健康老年人）前瞻性纳入 50-66 岁青光眼患者和 10 名 38-82 岁青光眼患者。对于每个参与者，所有测量都是在一次会议中进行的。仰卧 5 分钟后，对双眼进行 5 次扫描。经过 5 分钟的坐姿适应后，在坐姿下进行了 5 次扫描。所有测量均使用同一仪器。使用组内相关系数 (ICC)、一致性相关系数 (ρ) 和 Bland-Altman 图评估 4 个 ONH 和 3 个 RNFL 参数的仰卧位和坐位测量之间的可重复性和相关性。结果 ONH（ICC 范围，73%–99%）和 RNFL（ICC 范围，72%–99%）参数的测量在单眼内具有高度可重复性。仰卧位和坐位 ONH 测量值之间的相关性很强，范围从 ρ = 97%–99%（年轻健康）到 ρ = 98%–99%（老年健康）和 ρ = 84%–99%（青光眼）。 Bland-Altman 图表明，ONH 和 RNFL 参数的坐位和仰卧位读数之间具有良好的一致性。结论 ONH 和 RNFL 测量的重复性很高，并且坐位和仰卧位之间的测量值高度相关。 iVue SD-OCT 在两种身体姿势下评估 ONH 和 RNFL 参数的能力都非常好。
PURPOSETo evaluate repeatability and positional independence of optic nerve head (ONH) and retinal nerve fiber layer (RNFL) thickness measurements in sitting and supine body positions using portable spectral-domain optical coherence tomography (iVue SD-OCT; Optovue Inc).DESIGNEvaluation of diagnostic technology.METHODSSixty eyes of 30 subjects (10 healthy younger adults aged 20–27 years, 10 healthy older adults aged 50–66 years, and 10 glaucoma patients aged 38–82 years) were included prospectively. For each participant, all measurements were taken in a single session. After 5 minutes in the supine position, 5 scans were obtained from both eyes. Following a 5-minute sitting adaptation, 5 scans were then obtained in the sitting position. The same instrument was used for all measurements. Repeatability and correlation between supine and sitting measurements of 4 ONH and 3 RNFL parameters were assessed using intraclass correlation coefficients (ICC), concordance correlation coefficients (ρ), and Bland-Altman plots.RESULTSMeasurements were highly repeatable within individual eyes, both for ONH (ICC range, 73%–99%) and RNFL (ICC range, 72%–99%) parameters. The correlation between supine and sitting ONH measurements was strong and ranged from ρ = 97%–99% (younger healthy) to ρ = 98%–99% (older healthy) and ρ = 84%–99% (glaucoma). Bland-Altman plots indicated good agreement between sitting and supine readings of ONH and RNFL parameters.CONCLUSIONSRepeatability of measurements of ONH and RNFL is high and measurements between sitting and supine are highly correlated. The ability of the iVue SD-OCT to evaluate ONH and RNFL parameters is good to excellent in both body positions.
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DOI：
10.1097/iae.0b013e3181dc048c
发表时间：
2010-04-01
期刊：
Retina (Philadelphia, Pa.)
影响因子：
--
作者：
Muni, Rajeev H;Kohly, Radha P;Lee, Thomas C
通讯作者：
Lee, Thomas C
影响因子：
--
作者：
Muni, Rajeev H.;Kohly, Radha P.;Lee, Thomas C.
通讯作者：
Lee, Thomas C.
影响因子：
4.1
作者：
Mansouri, Kaweh;Shaarawy, Tarek
通讯作者：
Shaarawy, Tarek
影响因子：
2
作者：
Hirooka, K;Shiraga, F
通讯作者：
Shiraga, F
影响因子：
0.4
作者：
Hayashi A;Yagou T;Nakamura T;Fujita K;Oka M;Fuchizawa C
通讯作者：
Fuchizawa C