Health outcomes of smoking during pregnancy and the postpartum period: an umbrella review.
Health outcomes of smoking during pregnancy and the postpartum period: an umbrella review.
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DOI：
10.1186/s12884-021-03729-1
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发表时间：
2021-03-26
影响因子：
3.1
通讯作者：
Jackson L
中科院分区：
文献类型：
--
作者：
Avşar TS;McLeod H;Jackson L
孕期（SDP）和产后吸烟对母亲和婴儿的健康有严重影响。尽管一些系统综述已经显示了母亲孕期吸烟对特定疾病的影响，但一篇审视整体健康结果的系统综述尚未发表。因此，本文旨在对这一问题进行综合综述。
按照提交给PROSPERO（CRD42018086350）的方案进行了系统综述的系统综述（综合综述）。检索了CINAHL、EMBASE、MEDLINE、PsycINFO、Web of Science、CRD数据库和HMIC数据库，纳入了截至2017年12月31日以英语发表的所有研究，但专门针对低收入国家的研究除外。两名研究人员独立进行研究选择和质量评估。
该综述纳入了64项研究，分析了母亲孕期吸烟与46种健康状况之间的关系。婴儿患婴儿猝死综合征、哮喘、死产、低出生体重和肥胖的风险增加幅度最大。孕期吸烟的影响与吸烟数量有关。根据因果关联分析，5种与母亲相关的状况和10种与婴儿相关的状况与孕期吸烟有因果联系。此外，一些研究报告了孕期吸烟对先兆子痫、妊娠剧吐和婴儿皮肤缺陷有保护作用。该综述指出了文献中在剂量 - 反应关联、暴露窗口期、产后吸烟方面存在的重要空白。
该综述表明，母亲孕期吸烟不仅与短期健康状况（如早产、唇腭裂）有关，还与一些可能产生终身有害影响的状况（如肥胖、智力障碍）有关。
这项综合综述对孕期吸烟的整体健康影响进行了全面分析。研究结果表明，在评估孕期吸烟对健康和成本的影响时，应考虑长期健康影响以及短期影响，因为不包括长期结果的研究将低估这一问题的严重程度。此外，针对吸烟孕妇的干预措施应考虑到因健康益处而减少吸烟对母亲和婴儿的影响，而不仅仅是戒烟。
网络版包含补充材料，网址为10.1186/s12884 - 021 - 03729 - 1
Smoking during pregnancy (SDP) and the postpartum period has serious health outcomes for the mother and infant. Although some systematic reviews have shown the impact of maternal SDP on particular conditions, a systematic review examining the overall health outcomes has not been published. Hence, this paper aimed to conduct an umbrella review on this issue. A systematic review of systematic reviews (umbrella review) was conducted according to a protocol submitted to PROSPERO (CRD42018086350). CINAHL, EMBASE, MEDLINE, PsycINFO, Web of Science, CRD Database and HMIC databases were searched to include all studies published in English by 31 December 2017, except those focusing exclusively on low-income countries. Two researchers conducted the study selection and quality assessment independently. The review included 64 studies analysing the relationship between maternal SDP and 46 health conditions. The highest increase in risks was found for sudden infant death syndrome, asthma, stillbirth, low birth weight and obesity amongst infants. The impact of SDP was associated with the number of cigarettes consumed. According to the causal link analysis, five mother-related and ten infant-related conditions had a causal link with SDP. In addition, some studies reported protective impacts of SDP on pre-eclampsia, hyperemesis gravidarum and skin defects on infants. The review identified important gaps in the literature regarding the dose-response association, exposure window, postnatal smoking. The review shows that maternal SDP is not only associated with short-term health conditions (e.g. preterm birth, oral clefts) but also some which can have life-long detrimental impacts (e.g. obesity, intellectual impairment). This umbrella review provides a comprehensive analysis of the overall health impacts of SDP. The study findings indicate that while estimating health and cost outcomes of SDP, long-term health impacts should be considered as well as short-term effects since studies not including the long-term outcomes would underestimate the magnitude of the issue. Also, interventions for pregnant women who smoke should consider the impact of reducing smoking due to health benefits on mothers and infants, and not solely cessation. The online version contains supplementary material available at 10.1186/s12884-021-03729-1.
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影响因子：
7.4
作者：
Banderali G;Martelli A;Landi M;Moretti F;Betti F;Radaelli G;Lassandro C;Verduci E
通讯作者：
Verduci E
影响因子：
5.5
作者：
Castles, A;Adams, EK;Boulton, ML
通讯作者：
Boulton, ML
Tourette综合征的产前危险因素：系统评价。
影响因子：
3.1
作者：
Chao TK;Hu J;Pringsheim T
通讯作者：
Pringsheim T
DOI：
10.1093/toxsci/kfq103
发表时间：
2010-08
期刊：
Toxicological sciences : an official journal of the Society of Toxicology
影响因子：
--
作者：
Bruin JE;Gerstein HC;Holloway AC
通讯作者：
Holloway AC
影响因子：
34.3
作者：
Caleyachetty, Rishi;Tait, Christopher A.;Echouffo-Tcheugui, Justin B.
通讯作者：
Echouffo-Tcheugui, Justin B.