Copulation activates Fos-like immunoreactivity in the male quail forebrain
Copulation activates Fos-like immunoreactivity in the male quail forebrain
复制标题
交配激活雄性鹌鹑前脑中的 Fos 样免疫反应性
DOI：
10.1016/s0166-4328(97)87581-x
复制
发表时间：
1997
影响因子：
2.7
通讯作者：
J. Balthazart
中科院分区：
文献类型：
--
作者：
S. Meddle;V. King;B. Follett;J. Wingfield;M. Ramenofsky;A. Foidart;J. Balthazart
它已被证明使用Fos免疫细胞化学，交配激活哺乳动物大脑中的特定细胞群。在这项研究之前，没有在鸟类中进行过类似的研究。在哺乳动物中，Fos已经确定了由生殖器（阴茎）/躯体感觉和嗅觉/犁鼻刺激激活的脑回路。当然，这种输入在鸟类中应该很少或没有作用（没有阴茎，嗅觉几乎没有作用），因此可以预期不同的反应。雄性日本鹌鹑（Coturnix japonica）被允许与成年雌性自由互动，并在每种情况下确认存在活跃的性行为，包括泄殖腔接触运动。对照组受试者接触一只家养小鸡（与成年鹌鹑大小相同），未观察到性行为。交配诱导Fos样免疫反应（FLI）细胞的出现在视前区，腹侧纹状体，部分archistriatum，和丘间核。诱导FLI细胞观察到整个吻尾侧范围内的视前区的男性从水平的隔中脑束的水平前连合，并在吻侧部分的下丘脑视上交叉的水平。FLI细胞不直接位于第三脑室附近，但位于距脑室壁500-1000 μm的内侧视前核外侧缘水平，或在更尾部的切片中，位于终纹床核腹外侧的位置。这是不太可能的Fos诱导雄性交配引起的内分泌变化，因为交配不影响血浆中的促黄体激素或睾酮水平。它的结论是，反应是由于交配相关的体感输入和/或来自女性的刺激。
It has been demonstrated using Fos immunocytochemistry that copulation activates specific cell populations in the mammalian brain. Prior to this study, no similar work has been carried out in birds. In mammals, Fos has identified brain circuits activated by genital (penile)/somatosensory and by olfactory/vomeronasal stimuli. Such inputs, of course, should play little or no role in birds (no penis, little or no role for olfaction) and a differential responsiveness could therefore be expected. Male Japanese quail (Coturnix japonica) were allowed to interact freely with adult females and the presence of active sexual behavior, including cloacal contact movements, was confirmed in each case. Control subjects were exposed to a domestic chick (same size as an adult quail) and no sexual behavior was observed. Copulation induced the appearance of Fos-like immunoreactive (FLI) cells in the preoptic area, the hyperstriatum ventrale, parts of the archistriatum, and the nucleus intercollicularis. Induction of FLI cells was observed throughout the rostral to caudal extent of the preoptic region of males from the level of the tractus septomesencephalicus to the level of the anterior commissure, and in the rostral part of the hypothalamus to the level of the supraoptic decussation. The FLI cells did not lie directly adjacent to the third ventricle, but were located 500–1000 μm from the ventricle wall at the level of the lateral edge of the medial preoptic nucleus or, in more caudal sections, in a position ventrolateral to the bed nucleus striae terminalis. It is unlikely that the Fos induction in males resulted from copulation-induced endocrine changes because copulation did not affect plasma levels of luteinizing hormone or testosterone. It is concluded that the responses were due to copulation-associated somatosensory inputs and/or to stimuli originating from the female.
影响因子：
56.9
作者：
SAGAR, SM;SHARP, FR;CURRAN, T
通讯作者：
CURRAN, T
在给予雄激素、雌激素或不给予类固醇替代的去势雄性大鼠中，交配诱导的神经 c-fos 免疫反应水平相当。
影响因子：
3.6
作者：
Baum,MJ;Wersinger,SR
通讯作者：
Wersinger,SR