On-demand, remote and lossless manipulation of biofluid droplets.

On-demand, remote and lossless manipulation of biofluid droplets.
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DOI:
10.1039/d2mh00695b
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发表时间:
2022-10-31
期刊:
影响因子:
13.3
通讯作者:
--
中科院分区:
材料科学1区
文献类型:
--
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最近全球爆发的流行病和大流行病向我们表明,我们应对传染病的准备严重不足。暴露于生物体液(例如血液、唾液、尿液等)中的传染源对临床实验室人员和医护人员构成严重风险,每年导致数亿例医院获得性和实验室获得性感染。通过远程和自动处理传染性生物体液来最大限度地减少人类接触的新技术将减轻这种风险。在这项工作中,我们提出了生物流体操纵器,它允许按需、远程和无损地操纵几乎任何液滴。我们的机械臂是通过将热响应软执行器与超全疏表面集成而设计的。利用我们的操纵器,我们演示了对生物流体液滴的按需、远程和无损操纵。我们设想,我们的生物流体机械臂不仅可以减少手动操作并最大程度地减少与传染性病原体的接触,而且还可以为开发廉价、简单和便携式机器人系统铺平道路,该系统可以实现即时护理操作,特别是在发展中国家。
The recent global outbreaks of epidemics and pandemics have shown us that we are severely under-prepared to cope with infectious agents. Exposure to infectious agents present in biofluids (e.g., blood, saliva, urine etc.) poses a severe risk to clinical laboratory personnel and healthcare workers, resulting in hundreds of millions of hospital-acquired and laboratory-acquired infections annually. Novel technologies that can minimize human exposure through remote and automated handling of infectious biofluids will mitigate such risk. In this work, we present biofluid manipulators, which allow on-demand, remote and lossless manipulation of virtually any liquid droplet. Our manipulators are designed by integrating thermo-responsive soft actuators with superomniphobic surfaces. Utilizing our manipulators, we demonstrate on-demand, remote and lossless manipulation of biofluid droplets. We envision that our biofluid manipulators will not only reduce manual operations and minimize exposure to infectious agents, but also pave the way for developing inexpensive, simple and portable robotic systems, which can allow point-of-care operations, particularly in developing nations.
DOI: 10.1902/jop.2003.74.6.858
发表时间: 2003-06-01
影响因子: 4.3
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DOI: 10.1007/978-1-59745-198-7_4
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影响因子: --
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影响因子: 41.2
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DOI: 10.1039/c6lc00673f
发表时间: 2016-01-01
期刊: LAB ON A CHIP
影响因子: 6.1
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