Dynamics of racial disparities in all-cause mortality during the COVID-19 pandemic.

Dynamics of racial disparities in all-cause mortality during the COVID-19 pandemic.
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DOI:
10.1073/pnas.2210941119
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发表时间:
2022-10-04
影响因子:
11.1
通讯作者:
--
中科院分区:
综合性期刊1区
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--
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随着记录 COVID-19 按种族和族裔不同影响的研究不断增多,人们很少关注大流行期间死亡率差异的动态以及差异的变化是否持续存在。我们估算了 2018 年 1 月至 2022 年 2 月美国七个种族/民族人口的年龄标准化每月全因死亡率。使用连接点回归,我们量化了种族特定比率相对于非西班牙裔白人死亡率的趋势,以检查与大流行相关的死亡率差异变化的程度。从 2018 年 1 月到 2020 年 2 月,大流行前的差异保持稳定。随着大流行的开始,美洲印第安人或阿拉斯加原住民 (AIAN)、夏威夷原住民或其他太平洋岛民 (NHOPI) 以及黑人的相对死亡率劣势增加,而亚裔和西班牙裔群体的相对死亡率优势下降。在 COVID-19 激增期间,比率普遍上升,2021 年夏季和 2021/2022 年冬季激增的模式有所不同,当时亚洲人和黑人的差异接近大流行前的水平。然而,在这些激增期间,有两个 65 岁以下人群的表现比白人更差。对于 AIAN 人群,2021 年 10 月观察到的比率达到 2.25 (95% CI = 2.14, 2.37),而大流行前平均值为 1.74 (95% CI = 1.62, 1.86);对于 NHOPI 人群,2021 年 8 月观察到的比率达到 2.12 (95% CI = 1.92, 2.33),而大流行前平均值为 1.74 (95% CI = 1.62, 1.86)。大流行前平均值为 1.31 (95% CI = 1.13, 1.49)。我们的研究结果强调了种族/族裔死亡率差异的动态性质,并对大流行造成的原住民群体死亡率不平等现象的加剧提出了警告。
As research documenting disparate impacts of COVID-19 by race and ethnicity grows, little attention has been given to dynamics in mortality disparities during the pandemic and whether changes in disparities persist. We estimate age-standardized monthly all-cause mortality in the United States from January 2018 through February 2022 for seven racial/ethnic populations. Using joinpoint regression, we quantify trends in race-specific rate ratios relative to non-Hispanic White mortality to examine the magnitude of pandemic-related shifts in mortality disparities. Prepandemic disparities were stable from January 2018 through February 2020. With the start of the pandemic, relative mortality disadvantages increased for American Indian or Alaska Native (AIAN), Native Hawaiian or other Pacific Islander (NHOPI), and Black individuals, and relative mortality advantages decreased for Asian and Hispanic groups. Rate ratios generally increased during COVID-19 surges, with different patterns in the summer 2021 and winter 2021/2022 surges, when disparities approached prepandemic levels for Asian and Black individuals. However, two populations below age 65 fared worse than White individuals during these surges. For AIAN people, the observed rate ratio reached 2.25 (95% CI = 2.14, 2.37) in October 2021 vs. a prepandemic mean of 1.74 (95% CI = 1.62, 1.86), and for NHOPI people, the observed rate ratio reached 2.12 (95% CI = 1.92, 2.33) in August 2021 vs. a prepandemic mean of 1.31 (95% CI = 1.13, 1.49). Our results highlight the dynamic nature of racial/ethnic disparities in mortality and raise alarm about the exacerbation of mortality inequities for Indigenous groups due to the pandemic.
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发表时间: 2022-02-16
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