Identifying RNA editing sites using RNA sequencing data alone.
Identifying RNA editing sites using RNA sequencing data alone.
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DOI:
10.1038/nmeth.2330
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发表时间:
2013-02
期刊:
影响因子:
48
通讯作者:
Li, Jin Billy
中科院分区:
文献类型:
--
作者:
Ramaswami, Gokul;Zhang, Rui;Piskol, Robert;Keegan, Liam P.;Deng, Patricia;O'Connell, Mary A.;Li, Jin Billy
We show that RNA editing sites can be called with high confidence using RNA sequencing data from multiple samples across either individuals or species, without the need for matched genomic DNA sequence. We identified many previously unidentified editing sites in both humans and Drosophila; our results nearly double the known number of human protein recoding events. We also found that human genes harboring conserved editing sites within Alu repeats are enriched for neuronal functions.
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影响因子:
4.5
作者:
Kleinman, Claudia L.;Adoue, Veronique;Majewski, Jacek
通讯作者:
Majewski, Jacek
DOI:
10.1126/science.1207018
发表时间:
2011-07-01
期刊:
Science (New York, N.Y.)
影响因子:
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作者:
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通讯作者:
Cheung VG
影响因子:
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作者:
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影响因子:
56.9
作者:
Hoopengardner, B;Bhalla, T;Reenan, R
通讯作者:
Reenan, R
影响因子:
16.6
作者:
Nishikura K
通讯作者:
Nishikura K