TraceLink: A model of amnesia and consolidation of memory
TraceLink: A model of amnesia and consolidation of memory
复制标题
TraceLink：健忘症和记忆巩固模型
作者：
J. Murre
引入了一种称为 TraceLink 的健忘症模型，该模型由三个系统组成：1）跟踪系统（新皮质），2）链接系统（海马体），3）调节系统（海马体/穹窿/基底前脑）。它旨在解释健忘症神经心理学的重要方面，例如逆行性健忘症中的 Ribot 梯度、顺行性和逆行性健忘症之间的分离模式、健忘症的恢复，以及由某些不影响海马的颞叶病变引起的新发现的健忘症形式（语义痴呆）。此外，该模型基于大脑旨在最小化连接量的假设，为海马体和新皮质的整体神经解剖学提供了新的解释。它还提供了各种巩固记忆的策略，其效果在计算机模拟中得到了探索。该论文最后给出了来自 TraceLink 模型的 10 个基本上未经测试的预测。 © 1997 Wiley-Liss, Inc.
A model of amnesia is introduced, called TraceLink, that consists of three systems: 1) a trace system (neocortex), 2) a link system (hippocampus), and 3) a modulatory system (hippocampus/fornix/basal forebrain). It aims to explain salient aspects of the neuropsychology of amnesia, such as Ribot gradients in retrograde amnesia, patterns of dissociation between anterograde and retrograde amnesia, recovery from amnesia, and a newly discovered form of amnesia (semantic dementia) that results from certain temporal lobe lesions that do not affect the hippocampus. The model, furthermore, offers a new explanation for the global neuroanatomy of the hippocampus and neocortex based on the assumption that the brain aims to minimize connectivity volume. It also offers various strategies for the consolidation of memory, the effects of which are explored in computer simulations. The paper concludes with ten, largely untested, predictions derived from the TraceLink model. © 1997 Wiley‐Liss, Inc.
影响因子：
3.7
作者：
Felleman, Daniel J.;Van Essen, David C.
通讯作者：
Van Essen, David C.
影响因子：
56.9
作者：
KNOWLTON, BJ;SQUIRE, LR
通讯作者：
SQUIRE, LR
DOI：
10.1073/pnas.91.15.7041
发表时间：
1994-07-19
影响因子：
11.1
作者：
ALVAREZ, P;SQUIRE, LR
通讯作者：
SQUIRE, LR