Morphological and functional changes in spectral domain optical coherence tomography and microperimetry in macular microhole variants: spectral domain optical coherence tomography and microperimetry correlation.

Morphological and functional changes in spectral domain optical coherence tomography and microperimetry in macular microhole variants: spectral domain optical coherence tomography and microperimetry correlation.
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DOI:
10.4103/0301-4738.91347
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发表时间:
2012-01
影响因子:
3.1
通讯作者:
Sharma T
Sharma T
中科院分区:
医学4区
文献类型:
--
作者:
Gella L;Raman R;Pal SS;Nittala MG;Sharma T

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目的探讨黄斑区变异性微孔(MMH)形态与视网膜功能的关系。我们对11例(12只眼)感光层IS/OS交界处缺陷的患者进行了光谱域光学相干断层扫描(SD-OCT)和微视野检查。患眼的平均logMAR视力为0.15 ± 0.17(范围0.00-0.5)。MMH水平直径平均为163 ± 99 μm,对应区域的视网膜敏感度平均为13.79 ± 4.6dB。MMH直径与视网膜敏感度呈负相关(r =-0.65,p = 0.02)。三种形态学模式的MMH变体上SD-OCT识别,这并没有不同的视网膜敏感性。我们对MMH的变异体进行了描述和分类,并利用微视野对MMH的生理功能进行了评价。
To evaluate the relationship between the morphology and retinal function of macular microhole (MMH) variants. We evaluated 12 eyes of 11 patients with defects in the IS/OS junction of photoreceptor layer with SD-OCT. All patients underwent comprehensive ophthalmic examination including spectral domain optical coherence tomography (SD-OCT) and microperimetry. The mean logMAR visual acuity in the affected eye was 0.15 ± 0.17 (range 0.00–0.5). Mean horizontal diameter of the MMH was 163 ± 99 μm; the mean retinal sensitivity in the area corresponding to the MMH was 13.79 ± 4.6 dB. Negative correlation was found between the MMH diameter and the retinal sensitivity (r = -0.65, p = 0.02). Three morphological patterns of MMH variants were recognized on SD-OCT, which did not differ in retinal sensitivities. We described and classified the MMH variants and made an assessment on the physiological functions using microperimeter.
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