Effect of immunization with lutropin-receptor on the ovarian function of rabbits.
Effect of immunization with lutropin-receptor on the ovarian function of rabbits.
复制标题
促黄体素受体免疫对家兔卵巢功能的影响。
DOI:
10.1080/15321819508013546
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发表时间:
1995
期刊:
影响因子:
--
通讯作者:
Saxena,BB
中科院分区:
文献类型:
--
作者:
Singh,M;Lin,SQ;Saxena,BB
Three New Zealand white adult female rabbits, designated as A, B, and C, were immunized to produce lutropin receptor antibodies. Antisera inhibited the binding of125I-hCG to the lutropin receptor and the production of testosterone by hCG stimulated rat Leydig cells. During the study period of, approximately 10 months after the last immunization, rabbits did not ovulate in response to an injection of 75 IU of human chorionic gonadotropin or mating as revealed by laparotomy. As the antibody titers declined, induction of ovulation and laparotomy revealed restoration of ovulation and corpus luteum formation. However, no pregnancy occurred when rabbits A and B were mated and artificially inseminated. These observations indicate that lutropin receptor antibodies can cause infertility in female rabbits.
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影响因子:
6.1
作者:
B. Saxena;Mukul Singh
通讯作者:
Mukul Singh
影响因子:
2.9
作者:
B. Saxena;B. Dattatreyamurty;H. Ota;V. Milkov;P. Rathnam
通讯作者:
P. Rathnam
影响因子:
1.3
作者:
B. Saxena;R. Landesman;G. Gupta;Mukul Singh;P. Rathnam;B. Dattatreyamurty
通讯作者:
B. Dattatreyamurty
影响因子:
9.8
作者:
R. Glass;A. Mroueh
通讯作者:
A. Mroueh
DOI:
10.1210/jcem-36-1-148
发表时间:
1973
期刊:
The Journal of Clinical Endocrinology and Metabolism
影响因子:
--
作者:
C. Y. Lee;C. Coulam;N. Jiang;R. Ryan
通讯作者:
R. Ryan