Energy compensation and adiposity in humans.
Energy compensation and adiposity in humans.
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DOI：
10.1016/j.cub.2021.08.016
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发表时间：
2021-10-25
期刊：
影响因子：
--
通讯作者：
IAEA DLW database group
中科院分区：
文献类型：
--
作者：
Careau V;Halsey LG;Pontzer H;Ainslie PN;Andersen LF;Anderson LJ;Arab L;Baddou I;Bedu-Addo K;Blaak EE;Blanc S;Bonomi AG;Bouten CVC;Buchowski MS;Butte NF;Camps SGJA;Close GL;Cooper JA;Das SK;Cooper R;Dugas LR;Eaton SD;Ekelund U;Entringer S;Forrester T;Fudge BW;Goris AH;Gurven M;Hambly C;El Hamdouchi A;Hoos MB;Hu S;Joonas N;Joosen AM;Katzmarzyk P;Kempen KP;Kimura M;Kraus WE;Kushner RF;Lambert EV;Leonard WR;Lessan N;Martin CK;Medin AC;Meijer EP;Morehen JC;Morton JP;Neuhouser ML;Nicklas TA;Ojiambo RM;Pietiläinen KH;Pitsiladis YP;Plange-Rhule J;Plasqui G;Prentice RL;Rabinovich RA;Racette SB;Raichlen DA;Ravussin E;Reilly JJ;Reynolds RM;Roberts SB;Schuit AJ;Sjödin AM;Stice E;Urlacher SS;Valenti G;Van Etten LM;Van Mil EA;Wells JCK;Wilson G;Wood BM;Yanovski J;Yoshida T;Zhang X;Murphy-Alford AJ;Loechl CU;Luke AH;Rood J;Sagayama H;Schoeller DA;Wong WW;Yamada Y;Speakman JR;IAEA DLW database group
了解活动对能量平衡的影响至关重要。活动水平的增加可能会导致能量消耗的收益递减，因为非活动能量消耗的补偿反应。这一建议对新陈代谢的进化和人类健康都有深远的影响。这意味着活动的长期增加并不直接转化为总能量消耗（TEE）的增加，因为TEE的其他成分可能会减少反应能量补偿。我们使用了对正常生活的成年人TEE和BEE（N = 1，754）进行编译的最大数据集，发现由于BEE减少，典型人类的能量补偿平均为28%;这表明我们从额外活动中燃烧的额外卡路里中只有72%转化为当天燃烧的额外卡路里。此外，不同身体组成的人之间的能量补偿程度差异很大。补偿和肥胖之间的这种联系可能是由于补偿的个体差异：补偿更多的人可能更容易积累身体脂肪。或者，这个过程可能发生在个体内部：随着我们变胖，我们的身体可能会更强烈地补偿活动期间燃烧的卡路里，从而使减肥变得越来越困难。确定能量补偿和肥胖之间的因果关系将是改善肥胖公共卫生策略的关键。
Understanding the impacts of activity on energy balance is crucial. Increasing levels of activity may bring diminishing returns in energy expenditure because of compensatory responses in non-activity energy expenditures. This suggestion has profound implications for both the evolution of metabolism and human health. It implies that a long-term increase in activity does not directly translate into an increase in total energy expenditure (TEE) because other components of TEE may decrease in response–energy compensation. We used the largest dataset compiled on adult TEE and BEE (N = 1,754) of people living normal lives to find that energy compensation by a typical human averages 28% due to reduced BEE; this suggests that only 72% of the extra calories we burn from additional activity translate into extra calories burned that day. Moreover, the degree of energy compensation varied considerably between people of different body composition. This association between compensation and adiposity could be due to among-individual differences in compensation: people who compensate more may be more likely to accumulate body fat. Alternatively, the process might occur within individuals: as we get fatter, our body might compensate more strongly for the calories burned during activity, making losing fat progressively more difficult. Determining the causality of the relationship between energy compensation and adiposity will be key to improving public health strategies regarding obesity.
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影响因子：
3.1
作者：
Hand, Gregory A.;Shook, Robin P.;Blair, Steven N.
通讯作者：
Blair, Steven N.
影响因子：
16.8
作者：
Mathot, Kimberley J.;Dingemanse, Niels J.
通讯作者：
Dingemanse, Niels J.
影响因子：
1.6
作者：
Halsey, Lewis G.
通讯作者：
Halsey, Lewis G.
影响因子：
2.1
作者：
Breheny, Patrick;Burchett, Woodrow
通讯作者：
Burchett, Woodrow
DOI：
10.1016/j.cub.2015.12.046
发表时间：
2016-02-08
期刊：
Current biology : CB
影响因子：
--
作者：
Pontzer H;Durazo-Arvizu R;Dugas LR;Plange-Rhule J;Bovet P;Forrester TE;Lambert EV;Cooper RS;Schoeller DA;Luke A
通讯作者：
Luke A