The increased risk of sarcopenia in patients with cardiovascular risk factors in Suburb-Dwelling older Chinese using the AWGS definition.
The increased risk of sarcopenia in patients with cardiovascular risk factors in Suburb-Dwelling older Chinese using the AWGS definition.
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使用 AWGS 定义，居住在郊区的中国老年人有心血管危险因素的患者患肌少症的风险增加
DOI：
10.1038/s41598-017-08488-8
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发表时间：
2017-08-29
影响因子：
4.6
通讯作者：
Guo Q
中科院分区：
文献类型：
--
作者：
Han P;Yu H;Ma Y;Kang L;Fu L;Jia L;Chen X;Yu X;Hou L;Wang L;Zhang W;Yin H;Niu K;Guo Q
本研究旨在探讨中国老年人肌肉减少症与心血管危险因素（CVRF）的关系。本研究共纳入1611名年龄≥60岁的老年人。对糖尿病、高血压和血脂异常的CVRF进行了评估。肌少症是根据亚洲肌少症工作组（AWGS）推荐的算法定义的。采用多元logistic回归分析和线性回归对老年肌少症患者的CVRF组成及CVRF个数进行评价。在对潜在混杂因素进行调整后，CVRF与中国老年人群中肌肉减少症的高发率有关。此外，糖尿病和高血压，而不是血脂异常，被发现与肌肉减少症显著相关。具有CVRF 1、2和3个特征的参与者肌肉减少症的OR和95% CI分别为2.27（1.14-4.48）、4.13（1.80-9.46）和4.90（1.01-23.81）。骨骼肌减少症患病率的线性增加与老年人群中CVRF成分的数量有关（趋势的P值< 0.001）。了解已知的CVRF，特别是糖尿病和高血压，可能有助于预测老年人肌肉减少症的风险。
The aim of the present study is to investigate the relationship between sarcopenia and cardiovascular risk factors (CVRF) in the Chinese elderly. A total of 1611 elderly individuals aged ≥60 years were enrolled in this study. The well-established CVRF of diabetes, hypertensions, and dyslipidemia were assessed. Sarcopenia was defined according to the recommended algorithm of the Asian Working Group for Sarcopenia (AWGS). Multiple logistic regression analyses and the linear regressions were used to evaluate the components of CVRF and the number of CVRF of elderly patients with sarcopenia. After adjusting for potential confounders, CVRF was associated with a high prevalence of sarcopenia in elderly Chinese populations. Furthermore, diabetes and hypertension, but not dyslipidemia, were found to be significantly associated with sarcopenia. The OR and 95% CI for sarcopenia of the participants with 1, 2, and 3 features of CVRF were 2.27(1.14–4.48), 4.13(1.80–9.46), and 4.90(1.01–23.81), respectively. A linear increase in the prevalence of sarcopenia was found to be associated with the number of CVRF components in the elderly population (P values for the trends < 0.001). Knowledge of known CVRF, particularly diabetes and hypertension, may help predict the risk for sarcopenia in the elderly.
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DOI：
10.1093/gerona/gln018
发表时间：
2009-01
期刊：
The journals of gerontology. Series A, Biological sciences and medical sciences
影响因子：
--
作者：
Dalal M;Ferrucci L;Sun K;Beck J;Fried LP;Semba RD
通讯作者：
Semba RD
DOI：
10.1093/gerona/gln038
发表时间：
2009-04-01
影响因子：
5.1
作者：
Brinkley, Tina E.;Leng, Xiaoyan;Nicklas, Barbara J.
通讯作者：
Nicklas, Barbara J.
影响因子：
6.7
作者：
Narici, Marco V.;Maffulli, Nicola
通讯作者：
Maffulli, Nicola
影响因子：
3.7
作者：
Han K;Park YM;Kwon HS;Ko SH;Lee SH;Yim HW;Lee WC;Park YG;Kim MK;Park YM
通讯作者：
Park YM
使用亚洲肌肉减少症定义工作组研究居住在郊区的中国老年人中肌肉减少症的患病率和相关因素
DOI：
10.1093/gerona/glv108
发表时间：
2016-04-01
影响因子：
5.1
作者：
Han, Peipei;Kang, Li;Niu, Kaijun
通讯作者：
Niu, Kaijun