Level of and associated factors for non-adherence to anti-tuberculosis treatment among tuberculosis patients in Gamo Gofa zone, southern Ethiopia: cross-sectional study.
Level of and associated factors for non-adherence to anti-tuberculosis treatment among tuberculosis patients in Gamo Gofa zone, southern Ethiopia: cross-sectional study.
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DOI：
10.1186/s12889-020-09827-7
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发表时间：
2020-11-13
影响因子：
4.5
通讯作者：
Gebeyehu S
中科院分区：
文献类型：
--
作者：
Ajema D;Shibru T;Endalew T;Gebeyehu S
不坚持抗结核治疗是改善结核病（TB）治疗结果和降低医疗费用的关键挑战之一。结核病患者坚持抗结核治疗的情况不佳是埃塞俄比亚的一个主要问题。本研究旨在评估加莫戈法地区结核病患者不坚持抗结核治疗的水平和相关因素。2017年7月20日至8月30日在Gamo Gofa区进行了一项横断面研究。采用了多阶段抽样技术。该研究包括289名正在接受抗结核治疗的患者。数据是由受过训练的数据收集者通过访谈使用结构化和预先测试的问卷收集的。使用SPSS 23拟合多元逻辑回归模型，以确定与不坚持抗结核治疗相关的因素，其显著性水平为5%。我们发现，16.5%的参与者未坚持抗结核治疗。未向家人透露结核病状况（AOR = 31.7; 95% CI：9.1-111.1），无预期不良事件信息（AOR = 31.1; 95% CI：7.5-128.3），既往抗结核治疗史吸烟（AOR = 5.3; 95%CI：1.5-18.8）和吸烟（AOR = 11.7; 95%CI：3.2-43.03）与不依从抗结核治疗的几率较高相关。结核病患者中不坚持抗结核治疗的比例很高。卫生保健提供者应就预期的不良事件和患者面临预期不良事件时应采取的措施向结核病患者提供咨询。他们亦应劝谕病人向家人透露其结核病情况，并停止吸烟。在线版本包含补充材料，可通过10.1186/s12889-020-09827-7获得。
Non-adherence to anti-TB treatment is one of the crucial challenges in improving tuberculosis (TB) treatment outcomes and reducing healthcare costs. The poor adherence to anti-TB treatment among patients with TB is a major problem in Ethiopia. This study aimed to assess the level of and associated factors for non-adherence to anti-TB therapy among patients with tuberculosis in the Gamo Gofa Zone. A cross-sectional study was conducted at Gamo Gofa Zone from July 20 – August 30, 2017. A multi-stage sampling technique was used. The study included 289 patients who were on anti-TB treatment. Data were collected by trained data collectors using a structured and pre-tested questionnaire through interviews. A multiple logistic regression model was fitted using SPSS 23 to identify factors associated with non-adherence to anti-TB treatment at a 5% significance level. We found that 16.5% of the participants were non-adherent for anti-TB treatment. Failure to disclose one’s TB status to his or her family (AOR = 31.7; 95% CI: 9.1–111.1), having no information on the expected adverse events (AOR = 31.1; 95% CI: 7.5–128.3), past anti-TB treatment history (AOR = 5.3; 95% CI: 1.5–18.8) and a smoking cigarette (AOR = 11.7; 95% CI: 3.2–43.03) were found to be associated with a higher odds of being non-adherent to anti-TB treatment. The level of non-adherence to anti-TB treatment among TB patients was high. Health care providers should counsel TB patients on the expected adverse events and measures to be taken when patients face the expected adverse events. They should also counsel their patients to disclose their TB status to his or her family and for ceasing cigarette smoking. The online version contains supplementary material available at 10.1186/s12889-020-09827-7.
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影响因子：
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作者：
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