Centrifugal Casting of Microfluidic Components With PDMS
Centrifugal Casting of Microfluidic Components With PDMS
复制标题
使用 PDMS 离心铸造微流体组件
DOI：
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发表时间：
2013
期刊：
影响因子：
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通讯作者：
D. Hardt
中科院分区：
文献类型：
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作者：
Aaron D. Mazzeo;D. Hardt
这项工作描述了离心铸造和快速固化的双面，聚二甲基硅氧烷（PDMS）为基础的组件与微观特征。离心铸造允许同时对部件的多个侧面进行图案化，并且允许在封闭模具中控制部件的厚度，而不会截留气泡。将填充有PDMS的模具以每分钟数千转的速度旋转几分钟，导致PDMS内捕获的气泡朝向旋转轴迁移或溶解到溶液中。为了快速固化部件（<10分钟），在完成纺丝后，有源元件加热和冷却填充有PDMS的腔体。由该方法产生的微流体通道具有低的变异系数（对于在20个部分中测量的通道的高度和宽度，<2%）。该工艺还能够在部件的相对侧中模制功能通道，如通过具有多层软光刻典型的阀系统的装置所证明的。
This work describes the centrifugal casting and fast curing of double-sided, polydimethylsiloxane (PDMS)-based components with microfeatures. Centrifugal casting permits simultaneous patterning of multiple sides of a component and allows control of the thickness of the part in an enclosed mold without entrapment of bubbles. Spinning molds filled with PDMS at thousands of revolutions per minute for several minutes causes entrapped bubbles within the PDMS to migrate toward the axis of rotation or dissolve into solution. To cure the parts quickly (<10 min), active elements heat and cool cavities filled with PDMS after the completion of spinning. Microfluidic channels produced from the process have a low coefficient of variation (<2% for the height and width of channels measured in 20 parts). This process is also capable of molding functional channels in opposite sides of a part as demonstrated through a device with a system of valves typical to multilayer soft lithography.
影响因子：
56.9
作者：
Unger, MA;Chou, HP;Quake, SR
通讯作者：
Quake, SR
影响因子：
7.4
作者：
Fu, AY;Chou, HP;Quake, SR
通讯作者：
Quake, SR