Engineering Biology: Model Conceptualisation and Realisation
Engineering Biology: Model Conceptualisation and Realisation
复制标题
工程生物学:模型概念化和实现
DOI:
10.1177/002029401104400604
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发表时间:
2011
影响因子:
2
通讯作者:
Imms R
中科院分区:
文献类型:
--
作者:
Imms R
A model of the lysis-lysogeny decision cycle of the Phage-λ virus has been re-implemented using standard engineering tools. The model is based on previous systems biology-based work and is constructed using the biological knowledge of the protein signalling networks within the virus. It explores how the emergent effects from the protein interactions produce the observed lysis-lysogeny behaviour. The software tools used (LabVIEWTM and MATLABTM) were chosen as they do not require specialised biochemical knowledge and have a wide industrial user base. This modelling is done as part of Project Fallot at Loughborough University, which is producing multiscale models of congenital heart disease. Part of this research requires a model of Delta-Notch protein signalling. Comment is made on the applications of the implemented modelling technique for modelling of Delta Notch protein signalling in cells.
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DOI:
10.1042/bst0330507
发表时间:
2005
期刊:
Biochemical Society transactions.
影响因子:
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作者:
Wolkenhauer,O;Sreenath,SN;Wellstead,P;Ullah,M;Cho,K-H
通讯作者:
Cho,K-H
DOI:
--
发表时间:
2007
期刊:
影响因子:
--
作者:
Hiroyuki Kuwahara
通讯作者:
Hiroyuki Kuwahara
DOI:
--
发表时间:
2010
期刊:
2010 Annual International Conference of the IEEE Engineering in Medicine and Biology
影响因子:
--
作者:
R. Summers;T. Abdulla;Ryan A. Imms;G. Carrault;Alfredo I. Hernández;L. Houyel;J. Schleich
通讯作者:
J. Schleich
DOI:
--
发表时间:
2006
期刊:
Trans. Comp. Sys. Biology
影响因子:
--
作者:
Hiroyuki Kuwahara;C. Myers;M. Samoilov;Nathan A. Barker;A. Arkin
通讯作者:
A. Arkin
影响因子:
--
作者:
H. Matsuno;Atsushi Doi;Masao Nagasaki;S. Miyano
通讯作者:
S. Miyano