Subtypes of stuttering determined by latent class analysis in two Swiss epidemiological surveys.
Subtypes of stuttering determined by latent class analysis in two Swiss epidemiological surveys.
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DOI：
10.1371/journal.pone.0198450
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发表时间：
2018
期刊：
影响因子：
3.7
通讯作者：
Howell P
中科院分区：
文献类型：
--
作者：
Ajdacic-Gross V;Bechtiger L;Rodgers S;Müller M;Kawohl W;von Känel R;Mutsch M;Rössler W;Seifritz E;Castelao E;Strippoli MF;Vandeleur C;Preisig M;Howell P
在两项大型流行病学研究中，研究了儿童口吃与广泛的危险因素、相关因素和合并症之间的关系。口吃的亚型，然后确定基于潜在类别分析（LCA）。数据来自两个具有代表性的瑞士人口样本：PsyCoLaus（N = 4，874，年龄35-82岁）和ZInEP流行病学调查（N = 1，500，年龄20-41岁）。在这两个样本中，研究了口吃与社会人口学特征、家庭聚集性、合并症和心理社会风险/相关因素之间的关系。LCAs对两个样本中报告童年时有口吃的人的选定项目进行了研究。最初的分析将早期焦虑症，如分离焦虑症和过度焦虑症与口吃联系起来（PsyCoLaus）。在这两个数据集中，ADHD都与口吃有关。在风险/相关因素的分析中，功能失调的父母关系，父母间的暴力和进一步的童年逆境是口吃的共同预测因子。此外，还观察到花粉热、哮喘、湿疹和银屑病的合并症（PsyCoLaus）。随后的LCA确定了一个非特异性的人群，他们自我报告说，他们口吃和一组定义的协会与心理社会逆境（ZINEP，PsyCoLaus）和特应性疾病（PsyCoLaus）。发展性口吃的两种亚型具有不同的危险/相关因素和共病模式。大多数因素与生命早期发生的脆弱性机制有关，也与其他神经发育障碍有关。心理社会因素和生物学因素似乎都参与了口吃的发病机制。
Associations between stuttering in childhood and a broad spectrum of risk factors, associated factors and comorbidities were examined in two large epidemiological studies. Subtypes of stuttering were then identified based on latent class analysis (LCA). Data were from two representative Swiss population samples: PsyCoLaus (N = 4,874, age 35–82 years) and the ZInEP Epidemiology Survey (N = 1,500, age 20–41 years). Associations between stuttering and sociodemographic characteristics, familial aggregation, comorbidity and psychosocial risk / associated factors were investigated in both samples. LCAs were conducted on selected items from people in both samples who reported having stuttered in childhood. Initial analyses linked early anxiety disorders, such as separation anxiety disorder and overanxious disorder, to stuttering (PsyCoLaus). ADHD was associated with stuttering in both datasets. In the analyses of risk / associated factors, dysfunctional parental relationships, inter-parental violence and further childhood adversities were mutual predictors of stuttering. Moreover, comorbidities were seen with hay fever, asthma, eczema and psoriasis (PsyCoLaus). Subsequent LCA identified an unspecific group of persons who self-reported that they stuttered and a group defined by associations with psychosocial adversities (ZINEP, PsyCoLaus) and atopic diseases (PsyCoLaus). The two subtypes of developmental stuttering have different risk / associated factors and comorbidity patterns. Most of the factors are associated with vulnerability mechanisms that occur early in life and that have also been linked with other neurodevelopmental disorders. Both psychosocial and biological factors appear to be involved in the etiopathogenesis of stuttering.
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影响因子：
4.7
作者：
Bright, Brianna C.;Soulakova, Julia N.
通讯作者：
Soulakova, Julia N.
DOI：
10.1044/1092-4388(2003/095
发表时间：
2003-10-01
影响因子：
2.6
作者：
Anderson, JD;Pellowski, MW;Kelly, EM
通讯作者：
Kelly, EM
DOI：
10.1017/s1121189x00006278
发表时间：
2005-04-01
期刊：
EPIDEMIOLOGIA E PSICHIATRIA SOCIALE
影响因子：
--
作者：
Angst, J;Gamma, A;Merikangas, KR
通讯作者：
Merikangas, KR
影响因子：
4.2
作者：
Berney, A;Preisig, M;Fenton, BT
通讯作者：
Fenton, BT
影响因子：
3.1
作者：
Ajdacic-Gross V;Aleksandrowicz A;Rodgers S;Mutsch M;Tesic A;Müller M;Kawohl W;Rössler W;Seifritz E;Castelao E;Strippoli MF;Vandeleur C;von Känel R;Paolicelli R;Landolt MA;Witthauer C;Lieb R;Preisig M
通讯作者：
Preisig M