Acquired fears reflected in cortical sensory processing: a review of electrophysiological studies of human classical conditioning.
Acquired fears reflected in cortical sensory processing: a review of electrophysiological studies of human classical conditioning.
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DOI:
10.1111/j.1469-8986.2012.01398.x
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发表时间:
2012-09
期刊:
影响因子:
3.7
通讯作者:
Keil A
中科院分区:
文献类型:
--
作者:
Miskovic V;Keil A
The capacity to associate neutral stimuli with affective value is an important survival strategy that can be accomplished by cell assemblies obeying Hebbian learning principles. In the neuroscience laboratory, classical fear conditioning has been extensively used as a model to study learning related changes in neural structure and function. Here, we review the effects of classical fear conditioning on electromagnetic brain activity in humans, focusing on how sensory systems adapt to changing fear-related contingencies. By considering spatio-temporal patterns of mass neuronal activity we illustrate a range of cortical changes related to a retuning of neuronal sensitivity to amplify signals consistent with fear-associated stimuli at the cost of other sensory information. Putative mechanisms that may underlie fear-associated plasticity at the level of the sensory cortices are briefly considered and several avenues for future work are outlined.
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影响因子:
9.2
作者:
Bauer, Markus;Kluge, Christian;Bach, Dominik;Bradbury, David;Heinze, Hans Jochen;Dolan, Raymond J.;Driver, Jon
通讯作者:
Driver, Jon
DOI:
10.1038/npp.2009.109
发表时间:
2010-01
期刊:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
影响因子:
--
作者:
通讯作者:
--
影响因子:
56.9
作者:
BEGLEITE.H;PLATZ, A
通讯作者:
PLATZ, A
影响因子:
5.5
作者:
BLISS, TVP;LOMO, T
通讯作者:
LOMO, T
影响因子:
1.9
作者:
Bradley, MA;Sabatinelli, D;Desai, P
通讯作者:
Desai, P