Allelic shift in cis-elements of the transcription factor RAP2.12 underlies adaptation associated with humidity in Arabidopsis thaliana.
Allelic shift in cis-elements of the transcription factor RAP2.12 underlies adaptation associated with humidity in Arabidopsis thaliana.
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DOI：
10.1126/sciadv.abn8281
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发表时间：
2022-05-06
期刊：
影响因子：
13.6
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中科院分区：
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广泛分布的物种的人口通常是通过对比压力的地理分布，但基本的遗传机制控制这种适应仍然是未知的。在这里，我们表明，在拟南芥中，等位基因的变化，顺式调控元件，WT盒和W盒，在启动子的关键转录因子与氧传感，相关AP 2.12（RAP 2.12），是负责差异调节耐旱性和洪水。这两个顺式元件受不同的转录因子调控，RAP 2.12下游导致缺氧应答转录物的差异积累。从一个顺式元件单倍型到另一个顺式元件单倍型的进化与从干旱生境到潮湿环境的定殖有关。因此，该基因通过一种适应机制促进干旱和洪水适应，该机制通过非编码等位基因使其调节多样化。拟南芥通过选择作用于氧敏感系统来适应潮湿环境。
Populations of widespread species are usually geographically distributed through contrasting stresses, but underlying genetic mechanisms controlling this adaptation remain largely unknown. Here, we show that in Arabidopsis thaliana, allelic changes in the cis-regulatory elements, WT box and W box, in the promoter of a key transcription factor associated with oxygen sensing, RELATED TO AP 2.12 (RAP2.12), are responsible for differentially regulating tolerance to drought and flooding. These two cis-elements are regulated by different transcription factors that downstream of RAP2.12 results in differential accumulation of hypoxia-responsive transcripts. The evolution from one cis-element haplotype to the other is associated with the colonization of humid environments from arid habitats. This gene thus promotes both drought and flooding adaptation via an adaptive mechanism that diversifies its regulation through noncoding alleles. Arabidopsis thaliana adapts to humid environments through selection acting on the oxygen-sensing system.
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影响因子：
16.6
作者：
Linster E;Stephan I;Bienvenut WV;Maple-Grødem J;Myklebust LM;Huber M;Reichelt M;Sticht C;Møller SG;Meinnel T;Arnesen T;Giglione C;Hell R;Wirtz M
通讯作者：
Wirtz M
影响因子：
11.6
作者：
Fukao, Takeshi;Yeung, Elaine;Bailey-Serres, Julia
通讯作者：
Bailey-Serres, Julia
影响因子：
10.7
作者：
Kumar, Sudhir;Stecher, Glen;Tamura, Koichiro
通讯作者：
Tamura, Koichiro
DOI：
10.1002/joc.5086
发表时间：
2017-10-01
期刊：
INTERNATIONAL JOURNAL OF CLIMATOLOGY
影响因子：
--
作者：
Fick, Stephen E.;Hijmans, Robert J.
通讯作者：
Hijmans, Robert J.
影响因子：
16.6
作者：
Cha JY;Kim WY;Kang SB;Kim JI;Baek D;Jung IJ;Kim MR;Li N;Kim HJ;Nakajima M;Asami T;Sabir JS;Park HC;Lee SY;Bohnert HJ;Bressan RA;Pardo JM;Yun DJ
通讯作者：
Yun DJ