Neurons in the lateral subdivision of the habenular complex mediate the hormonal onset of maternal behavior in rats.

Neurons in the lateral subdivision of the habenular complex mediate the hormonal onset of maternal behavior in rats.
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缰核复合体外侧细分的神经元介导大鼠母体行为的激素起始。

DOI:
10.1037//0735-7044.107.5.827
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发表时间:
1993
影响因子:
1.9
通讯作者:
Morrell,JI
Morrell,JI
中科院分区:
医学4区
文献类型:
--
作者:
Corodimas,KP;Rosenblatt,JS;Canfield,ME;Morrell,JI

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研究表明,射频诱导的缰复合体病变破坏了大鼠母性行为的激素发作,作者进一步探讨了缰复合体外侧(Lhb)亚部神经元对母性行为发作的重要性。在妊娠第12天,双侧细胞毒性病变产生的LHB与红藻氨酸或作为对照,只是背侧的内侧海马。第3组有射频诱导的Lhb和内侧(Mhb)病变。在妊娠第16天,Ss被切除卵巢,给予雌二醇,并在48小时后测试10天。然后使用荧光金神经解剖示踪直接量化Lhb神经元损失的程度和位置,并验证Mhb神经元是完整的。与对照组相比,整个LHB的细胞毒性病变阻止了母体行为的所有组成部分的发作。结果表明,在LHB,而不是MHB的神经元,是重要的大鼠母性行为的发病。(PsycINFO数据库记录(c)2016阿帕,保留所有权利)
Expanding on research showing that radio-frequency-induced lesions of the habenular complex disrupt the hormonal onset of maternal behavior in rats, the authors explored the importance of neurons in the lateral (Lhb) subdivision of the habenular complex for the onset of maternal behavior. On Day 12 of pregnancy, bilateral cytotoxic lesions were produced in the Lhb with kainic acid or, as a control, just dorsal in the medial hippocampus. A 3rd group had radio-frequency-induced Lhb and medial (Mhb) lesions. On Day 16 of pregnancy, Ss were hysterectomized–ovariectomized, given estradiol, and tested 48 hrs later for 10 days. Neuroanatomical tracing with fluoro-gold was then used to directly quantify the extent and location of Lhb neuron loss and to verify that Mhb neurons were intact. Cytotoxic lesions of the entire Lhb prevented the onset of all components of maternal behavior compared with controls. Results show that neurons in the Lhb, not the Mhb, are important for onset of maternal behavior in rats.(PsycINFO Database Record (c) 2016 APA, all rights reserved)
DOI: --
发表时间: 1987
影响因子: 2.5
作者:
M. Sabatino;G. Ferraro;N. Vella;V. Grutta
通讯作者: V. Grutta
处女和哺乳期大鼠的母性行为。
DOI: --
发表时间: 1974
期刊: Journal of Comparative and Physiological Psychology
影响因子: --
作者:
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通讯作者: J. Rosenblatt
DOI: --
发表时间: 1980
期刊: Brain Research
影响因子: 2.9
作者:
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DOI: 10.1037//0735-7044.97.6.873
发表时间: 1983-12
影响因子: 1.9
作者:
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DOI: 10.1523/jneurosci.12-08-03282.1992
发表时间: 1992-08-01
影响因子: 5.3
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HAUN, F;ECKENRODE, TC;MURRAY, M
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