A review on the diagnosis of animal trypanosomoses.
A review on the diagnosis of animal trypanosomoses.
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DOI：
10.1186/s13071-022-05190-1
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发表时间：
2022-02-19
影响因子：
3.2
通讯作者：
Berthier D
中科院分区：
文献类型：
--
作者：
Desquesnes M;Gonzatti M;Sazmand A;Thévenon S;Bossard G;Boulangé A;Gimonneau G;Truc P;Herder S;Ravel S;Sereno D;Jamonneau V;Jittapalapong S;Jacquiet P;Solano P;Berthier D
本文综述了诊断锥虫病的最可靠和最新方法，锥虫病是一组野生和家养哺乳动物的疾病，由锥虫（主要由昆虫传播的寄生虫鞭毛虫原生动物）引起。在非洲、美洲和亚洲，这些疾病在某些情况下影响人类，导致动物严重患病，并给牲畜造成重大经济损失。一些病原体在这篇评论中描述，包括几个唾液锥虫，如布氏锥虫sspp。（其中包括昏睡病的病原体，人类非洲锥虫[HAT]）、刚果锥虫和间日锥虫（引起“Nagana”或动物非洲锥虫病[AAT]）、伊氏锥虫（“Surra”）和马锥虫（“Dourine”），以及克氏锥虫，一种Stercorarian锥虫，美洲锥虫（恰加斯病）的病原体。用于检测在动物中引起恰加斯病和HAT的人畜共患锥虫的诊断方法，以及用于检测人类中的动物锥虫的诊断方法（所谓的“动物锥虫引起的非典型人类感染”[a-HT]），包括T. evansi和锥虫lewisi（大鼠寄生虫），也进行了审查。我们的目标是提出各种诊断方法和技术的综合观点，包括：（i）寄生虫检测;（ii）DNA检测;和（iii）抗体检测。讨论涵盖了需要考虑的各种其他因素，如各种诊断方法的灵敏度和特异性，可能在锥虫科中预期的关键交叉反应，其他补充信息，如临床观察和流行病学背景，研究规模以及后勤和成本限制。在特定的地理区域和环境中，讨论了使用几种技术检查多个标本和样品的适用性，以及技术人员面临的风险。本概述还讨论了诊断不同锥虫属和/或动体寄生虫混合感染的挑战。改善和加强全世界动物锥虫病的诊断程序将有助于更好地控制感染，并通过促进和保护动物、人类和环境健康，对“一个健康”产生重大影响。
This review focuses on the most reliable and up-to-date methods for diagnosing trypanosomoses, a group of diseases of wild and domestic mammals, caused by trypanosomes, parasitic zooflagellate protozoans mainly transmitted by insects. In Africa, the Americas and Asia, these diseases, which in some cases affect humans, result in significant illness in animals and cause major economic losses in livestock. A number of pathogens are described in this review, including several Salivarian trypanosomes, such as Trypanosoma brucei sspp. (among which are the agents of sleeping sickness, the human African trypanosomiasis [HAT]), Trypanosoma congolense and Trypanosoma vivax (causing “Nagana” or animal African trypanosomosis [AAT]), Trypanosoma evansi (“Surra”) and Trypanosoma equiperdum (“Dourine”), and Trypanosoma cruzi, a Stercorarian trypanosome, etiological agent of the American trypanosomiasis (Chagas disease). Diagnostic methods for detecting zoonotic trypanosomes causing Chagas disease and HAT in animals, as well as a diagnostic method for detecting animal trypanosomes in humans (the so-called “atypical human infections by animal trypanosomes” [a-HT]), including T. evansi and Trypanosoma lewisi (a rat parasite), are also reviewed. Our goal is to present an integrated view of the various diagnostic methods and techniques, including those for: (i) parasite detection; (ii) DNA detection; and (iii) antibody detection. The discussion covers various other factors that need to be considered, such as the sensitivity and specificity of the various diagnostic methods, critical cross-reactions that may be expected among Trypanosomatidae, additional complementary information, such as clinical observations and epizootiological context, scale of study and logistic and cost constraints. The suitability of examining multiple specimens and samples using several techniques is discussed, as well as risks to technicians, in the context of specific geographical regions and settings. This overview also addresses the challenge of diagnosing mixed infections with different Trypanosoma species and/or kinetoplastid parasites. Improving and strengthening procedures for diagnosing animal trypanosomoses throughout the world will result in a better control of infections and will significantly impact on “One Health,” by advancing and preserving animal, human and environmental health.
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DOI：
10.1186/1475-9292-5-2
发表时间：
2006-05-20
期刊：
Kinetoplastid biology and disease
影响因子：
--
作者：
Aradaib, Imadeldin E;Majid, Ali A
通讯作者：
Majid, Ali A
影响因子：
3.2
作者：
Birhanu H;Fikru R;Said M;Kidane W;Gebrehiwot T;Hagos A;Alemu T;Dawit T;Berkvens D;Goddeeris BM;Büscher P
通讯作者：
Büscher P
来自埃塞俄比亚式骆驼的新型锥虫埃文尼B型分离株。
影响因子：
3.8
作者：
Birhanu H;Gebrehiwot T;Goddeeris BM;Büscher P;Van Reet N
通讯作者：
Van Reet N
影响因子：
2.6
作者：
Boulange, Alain;Pillay, Davita;Baltz, Theo
通讯作者：
Baltz, Theo
影响因子：
2.6
作者：
Bossard, G.;Millogo, L.;Desquesnes, M.
通讯作者：
Desquesnes, M.