Education level is associated with neuropsychiatric symptoms in patients with amnestic‐mild cognitive impairment
Education level is associated with neuropsychiatric symptoms in patients with amnestic‐mild cognitive impairment
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教育水平与遗忘-轻度认知障碍患者的神经精神症状相关
DOI：
10.1111/psyg.12818
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发表时间：
2022
期刊：
影响因子：
2
通讯作者：
Shigeta Masahiro
中科院分区：
文献类型：
--
作者：
Inamura Keisuke;Shinagawa Shunichiro;Nagata Tomoyuki;Tagai Kenji;Nukariya Kazutaka;Shigeta Masahiro
背景我们检查了遗忘型轻度认知障碍 (a-MCI) 患者中神经精神症状 (NPS) 亚综合征的严重程度随教育水平的差异，目的是确定与 NPS 亚综合征相关的患者人口统计数据。 方法 总共纳入了 140 名 a-MCI 患者。我们根据患者的教育程度（小学教育、初中教育和高等教育）将患者分为三组，并比较他们的人口统计数据。为了根据教育水平探讨 NPS 亚综合征的严重程度，我们使用了调整简易精神状态检查 (MMSE) 评分后的神经精神量表 (NPI)。最后，使用一般线性模型 (GLM) 进一步探讨了被确定为与教育水平相关的 NPS 亚综合征。结果在三组之间观察到几个人口统计数据的显着差异。在NPS亚综合征中，初等和高等教育组的攻击性得分显着高于中等教育组，而初等教育组的冷漠/饮食问题得分显着高于其他组。 GLM 分析显示，攻击性与婚姻状况和 Zarit 看护者负担访谈 (ZBI-J) 评分有关，而冷漠/饮食问题与工具性日常生活活动 (IADL) 百分比、ZBI-J 评分和教育水平有关。 结论 在 NPS 亚综合征中，攻击性和冷漠/饮食问题根据 a-MCI 患者的教育水平而有所不同。 GLM 分析表明，在确定是否需要 NPS 干预措施时，不仅应考虑教育水平，还应考虑各种其他因素。
BackgroundWe examined differences in the severity of neuropsychiatric symptom (NPS) subsyndromes according to education level among patients with amnestic‐mild cognitive impairment (a‐MCI) with the aim of identifying patient demographics related to NPS subsyndromes.MethodsOverall, 140 patients with a‐MCI were included. We divided the patients into three groups according to their educational level (primary education, middle education, and high education) and compared their demographics. To explore the severity of NPS subsyndromes according to educational level, we used the Neuropsychiatric Inventory (NPI) after adjustments for the Mini‐Mental State Examination (MMSE) score. Finally, NPS subsyndromes that were identified as being related to educational level were further explored using a general linear model (GLM).ResultsSignificant differences in several demographics were observed among the three groups. Among the NPS subsyndromes, the scores for aggressiveness were significantly higher in the primary and high education groups than in the middle education group, while the apathy/eating problem scores were significantly higher in the primary education group than in the other groups. The GLM analyses showed that aggressiveness was related to marital status and the Zarit Caregiver Burden Interview (ZBI‐J) score, while apathy/eating problems were related to the instrumental activities of daily living (IADL) percentage, the ZBI‐J score, and the education level in years.ConclusionsAmong NPS subsyndromes, aggressiveness and apathy/eating problems differed according to education level in patients with a‐MCI. A GLM analysis suggested that not only education level, but also various other factors should be considered when determining the need for NPS interventions.
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期刊：
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影响因子：
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