Lab-on-a-Chip Sensor with Evaporated Bismuth Film Electrode for Anodic Stripping Voltammetry of Zinc.
Lab-on-a-Chip Sensor with Evaporated Bismuth Film Electrode for Anodic Stripping Voltammetry of Zinc.
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DOI：
10.1002/elan.201300349
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发表时间：
2013-12
期刊：
影响因子：
3
通讯作者：
Papautsky, Ian
中科院分区：
文献类型：
--
作者：
Kang, Wenjing;Pei, Xing;Yue, Wei;Bange, Adam;Heineman, William R.;Papautsky, Ian
在这项工作中，我们报告了一种芯片实验室电化学传感器的开发，该传感器使用蒸发铋电极通过方波阳极溶出伏安法检测锌。微型电化学电池由铋工作电极、集成银/氯化银参比电极和金辅助电极组成。该传感器在 pH 6 的 0.1 M 醋酸盐缓冲液中表现出线性响应，锌浓度范围为 1 μM 至 30 μM，计算检测限为 60 nM。该传感器还能够成功检测牛血清提取物中的锌，并通过独立的 AAS 测量验证结果。这些结果证明了这种芯片实验室电化学传感器在临床应用中的优势，包括样品量小（μL 级）、成本降低、响应时间短以及低浓度分析物下的高精度。
In this work, we report on the development of a lab-on-a-chip electrochemical sensor that uses an evaporated bismuth electrode to detect zinc using square wave anodic stripping voltammetry. The microscale electrochemical cell consists of a bismuth working electrode, an integrated silver/silver chloride reference electrode, and a gold auxiliary electrode. The sensor demonstrated linear response in 0.1 M acetate buffer at pH 6 with zinc concentrations ranging from 1 μM to 30 μM and a calculated detection limit of 60 nM. The sensor was also able to successfully detect zinc in a bovine serum extract and the results were verified with independent AAS measurements. These results demonstrate the advantageous qualities of this lab-on-a-chip electrochemical sensor for clinical applications, which include a small sample volume (μL scale), reduced cost, short response time and high accuracy at low concentrations of analyte.
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影响因子：
3
作者：
Jothimuthu, Preetha;Wilson, Robert A.;Herren, Josi;Pei, Xing;Kang, Wenjing;Daniels, Rodney;Wong, Hector;Beyette, Fred;Heineman, William R.;Papautsky, Ian
通讯作者：
Papautsky, Ian
影响因子：
6.1
作者：
Guo, ZY;Feng, F;Jaffrezic-Renault, N
通讯作者：
Jaffrezic-Renault, N
影响因子：
6.2
作者：
Lu, TH;Huang, JF;Sun, IW
通讯作者：
Sun, IW
影响因子：
2
作者：
Kumar, MP;Mouli, PC;Mohan, SV
通讯作者：
Mohan, SV
影响因子：
4.2
作者：
Ibs, KH;Rink, L
通讯作者：
Rink, L