Comprehensive Analyses of Transport Proteins Encoded Within the Genome of “Aromatoleum aromaticum” Strain EbN1
Comprehensive Analyses of Transport Proteins Encoded Within the Genome of “Aromatoleum aromaticum” Strain EbN1
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“Aromatoleumaromaticum”菌株 EbN1 基因组中编码的转运蛋白的综合分析
DOI:
10.1007/s00232-009-9168-2
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发表时间:
2009
影响因子:
2.4
通讯作者:
Saler MH Jr.
中科院分区:
文献类型:
--
作者:
Tamang DG;Rabus R;Barabote RD;Saler MH Jr.
The denitrifying bacterium “Aromatoleum aromaticum” strain EbN1 is specialized for the aerobic utilization of aromatic compounds including crude oil constituents. We here report whole-genome analyses for potential transport proteins inA. aromaticumstrain EbN1. This organism encodes very few transporters for simple sugars and most other common carbon sources. However, up to 28% of its putative transporters may act on fairly hydrophobic aromatic and aliphatic compounds. We categorize the putative transporters encoded within the genome, assign them to recognized families, and propose their preferred substrates. The bioinformatic data are correlated with available metabolic information to obtain an integrated view of the metabolic network ofA. aromaticumstrain EbN1. The results thus indicate that this organism possesses a disproportionately large percentage of transporters for the uptake and efflux of hydrophobic and amphipathic aromatic and aliphatic compounds compared with previously analyzed organisms. We predict that these findings will have important implications for our ecophysiological understanding of bioremediation.
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