Impact of cell wall encapsulation of almonds on in vitro duodenal lipolysis.

Impact of cell wall encapsulation of almonds on in vitro duodenal lipolysis.
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杏仁的细胞壁封装对体外十二指肠脂解的影响。

DOI:
10.1016/j.foodchem.2015.04.013
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发表时间:
2015-10-15
期刊:
影响因子:
8.8
通讯作者:
Ellis PR
Ellis PR
中科院分区:
农林科学1区
文献类型:
--
作者:
Grundy MM;Wilde PJ;Butterworth PJ;Gray R;Ellis PR

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组织微观结构控制杏仁体外脂解的速率和程度。 使用PH-STAT和GC分析的脂解方法很好地一致。 脂质生物可获得性的增加导致消化率的水平提高。 杏仁细胞壁限制了脂质释放,从而阻碍了消化动力学。 尽管杏仁的脂质含量很高,但它们的消耗与心血管疾病的风险降低有关。由于细胞壁基质充当上胃肠道上层消化的物理障碍,因此对这种悖论的一种解释可能是杏仁脂质的生物摄取性的限制。我们的目的是使用具有潜在不同程度的生物敏感性的原始和烤杏仁材料来测量体外十二指肠消化模型中脂解的速率和程度。结果表明,粒径减少导致脂解的速率和程度增加。粒径对脂质生物恢复性具有至关重要的影响,因为它是杏仁组织中破裂细胞比例的指标。具有完整细胞壁的分离的杏仁细胞显示出最低水平的消化率。这项研究强调了细胞壁调节脂质摄取的重要性,因此杏仁消耗的基本健康益处。
Tissue microstructure controlled rate and extent of in vitro lipolysis in almonds. Lipolysis methods using pH-stat and GC analysis were in good agreement. Increasing lipid bioaccessibility led to increased levels of digestibility. Almond cell walls restrict lipid release, thus hindering digestion kinetics. Although almonds have a high lipid content, their consumption is associated with reduced risk of cardiovascular disease. One explanation for this paradox could be limited bioaccessibility of almond lipids due to the cell wall matrix acting as a physical barrier to digestion in the upper gastrointestinal tract. We aimed to measure the rate and extent of lipolysis in an in vitro duodenum digestion model, using raw and roasted almond materials with potentially different degrees of bioaccessibility. The results revealed that a decrease in particle size led to an increased rate and extent of lipolysis. Particle size had a crucial impact on lipid bioaccessibility, since it is an indicator of the proportion of ruptured cells in the almond tissue. Separated almond cells with intact cell walls showed the lowest levels of digestibility. This study underlines the importance of the cell wall for modulating lipid uptake and hence the positive health benefits underlying almond consumption.
DOI: 10.1021/jf101325m
发表时间: 2010-07-14
影响因子: 6.1
作者:
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发表时间: 2003-08-29
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发表时间: 2008-05-14
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发表时间: 2012-08-01
影响因子: 7.1
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DOI: 10.3945/ajcn.114.088328
发表时间: 2015-01
期刊: The American journal of clinical nutrition
影响因子: --
作者:
Grundy MM;Grassby T;Mandalari G;Waldron KW;Butterworth PJ;Berry SE;Ellis PR
通讯作者: Ellis PR