The immunologic injury composite with balloon injury leads to dyslipidemia: a robust rabbit model of human atherosclerosis and vulnerable plaque.

The immunologic injury composite with balloon injury leads to dyslipidemia: a robust rabbit model of human atherosclerosis and vulnerable plaque.
复制标题

免疫损伤复合球囊损伤导致血脂异常:人类动脉粥样硬化和易损斑块的稳健兔模型

DOI:
10.1155/2012/249129
复制
发表时间:
2012
影响因子:
--
通讯作者:
Zhang J
Zhang J
中科院分区:
其他
文献类型:
--
作者:
Zhang G;Li M;Li L;Xu Y;Li P;Yang C;Zhou Y;Zhang J

文献摘要

参考文献

被引文献

相似文献

动脉粥样硬化是一种脂质沉积、血栓形成、免疫细胞浸润和慢性炎症反应的疾病,但由于缺乏合适的动物模型,特别是在草药领域,其系统研究受到阻碍。我们试图建立一个完美的动物模型,完全复制人类动脉粥样硬化的各个阶段。这是第一个基于胆固醇饮食的免疫损伤和球囊损伤的联合研究。在这项研究中,我们开发了一种改良的白色家兔模型,可以代表一种新的方法来研究人类动脉粥样硬化和易损斑块。
Atherosclerosis is a condition in which a lipid deposition, thrombus formation, immune cell infiltration, and a chronic inflammatory response, but its systemic study has been hampered by the lack of suitable animal models, especially in herbalism fields. We have tried to perform a perfect animal model that completely replicates the stages of human atherosclerosis. This is the first combined study about the immunologic injury and balloon injury based on the cholesterol diet. In this study, we developed a modified protocol of the white rabbit model that could represent a novel approach to studying human atherosclerosis and vulnerable plaque.
DOI: 10.3109/08941939.2011.557470
发表时间: 2011-04-01
影响因子: 1.9
作者:
Lazoura, Olga;Zacharoulis, Dimitris;Habib, Nagy
通讯作者: Habib, Nagy
DOI: 10.1016/s0008-6363(01)00467-9
发表时间: 2002-02-01
影响因子: 10.8
作者:
Matsuda, A;Suzuki, Y;Umemura, K
通讯作者: Umemura, K
DOI: 10.1159/000076646
发表时间: 2004-01-01
影响因子: 1.6
作者:
Nanobashvili, J;Prager, M;Huk, I
通讯作者: Huk, I
DOI: 10.1161/atvbaha.108.166173
发表时间: 2008-07-01
影响因子: 8.7
作者:
Calcagno, Claudia;Cornily, Jean-Christophe;Fayad, Zahi A.
通讯作者: Fayad, Zahi A.
使用针对血管内皮生长因子受体 2 的对比增强超声对家兔易损斑块进行分子成像
DOI: 10.1002/jcu.20759
发表时间: 2011-02-01
影响因子: 0.9
作者:
Liu, Hong;Wang, Xiang;Gao, Yun-Hua
通讯作者: Gao, Yun-Hua