High-risk features of basilar artery atherosclerotic plaque.
High-risk features of basilar artery atherosclerotic plaque.
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基底动脉粥样硬化斑块的高危特征
DOI：
10.3389/fneur.2022.1019036
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发表时间：
2022
影响因子：
3.4
通讯作者：
Wu, Li
中科院分区：
文献类型：
--
作者：
Li, Shaojun;Wei, Jiana;Huang, Ruiyun;Li, Chenghao;Chen, Hongbing;Qiu, Zhihua;Jiang, Yongjun;Wu, Li
关键词：
高分辨率磁共振成像（HR-MRI）用于表征动脉粥样硬化斑块。本研究旨在确定基底动脉（BA）粥样硬化斑块的高危特征。筛选晚期BA狭窄患者。通过高分辨率MRI评估纤维帽破裂（RFC）、脂质核心、斑块内出血（IPH）、斑块强化和钙化等特征。分析其与急性脑梗死的关系。从2014年6月1日至2018年12月31日，共纳入了143例患者，其中76例新发卒中。在25%的有症状患者和10.4%的无症状患者中发现RFC。48.7%的有症状患者和25.4%的无症状患者被确定为IPH。RFC（3.157，95% CI 1.062至9.382，p = 0.039）和IPH（2.78，95% CI 1.127至6.505，p = 0.026）是急性梗死的独立危险因素。本研究表明，动脉粥样硬化斑块的RFC和IPH是急性脑梗死的独立危险因素。
High-resolution magnetic resonance imaging (HR-MRI) is used to characterize atherosclerotic plaque. The present study aimed to determine the high-risk features of the basilar artery (BA) atherosclerotic plaque. Patients with advanced BA stenosis were screened. The features including the ruptured fibrous cap (RFC), lipid core, intraplaque hemorrhage (IPH), plaque enhancement, and calcification were assessed by using high-resolution MRI. The relationship between the features and acute infarction was analyzed. From 1 June 2014 to 31 December 2018, a total of 143 patients with 76 new strokes were included. RFC was identified in 25% of symptomatic and 10.4% of asymptomatic patients. IPH was identified in 48.7% of symptomatic and 25.4% of asymptomatic patients. RFC (3.157, 95% CI 1.062 to 9.382, p = 0.039) and IPH (2.78, 95% CI 1.127 to 6.505, p = 0.026) were independent risk factors for acute infarction. Our study showed that RFC and IPH of BA plaque were independent risk factors for acute infarction.
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DOI：
10.1016/j.jcmg.2016.06.017
发表时间：
2017-03
期刊：
JACC. Cardiovascular imaging
影响因子：
--
作者：
Sun J;Zhao XQ;Balu N;Neradilek MB;Isquith DA;Yamada K;Cantón G;Crouse JR 3rd;Anderson TJ;Huston J 3rd;O'Brien K;Hippe DS;Polissar NL;Yuan C;Hatsukami TS
通讯作者：
Hatsukami TS
椎基底动脉几何形态与动脉粥样硬化的关系
影响因子：
2.6
作者：
Yu J;Zhang S;Li ML;Ma Y;Dong YR;Lou M;Feng F;Gao S;Wu SW;Xu WH
通讯作者：
Xu WH
影响因子：
11.2
作者：
Xu, Wei-Hai;Li, Ming-Li;Cui, Li-Ying
通讯作者：
Cui, Li-Ying
高分辨率 MRI 低度和高度基底动脉狭窄斑块内出血的临床意义
DOI：
10.3174/ajnr.a5676
发表时间：
2018-07
期刊：
AJNR. American journal of neuroradiology
影响因子：
--
作者：
Zhu C;Tian X;Degnan AJ;Shi Z;Zhang X;Chen L;Teng Z;Saloner D;Lu J;Liu Q
通讯作者：
Liu Q
影响因子：
2.9
作者：
Hennerici, MG
通讯作者：
Hennerici, MG