Thermo-responsive behavior of propynyl-containing hydroxyethyl starch
Thermo-responsive behavior of propynyl-containing hydroxyethyl starch
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含丙炔基羟乙基淀粉的热响应行为
DOI：
10.1007/s00396-016-4009-1
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发表时间：
2017-02
影响因子：
2.4
通讯作者：
具本植
中科院分区：
文献类型：
--
作者：
具本植
Thermo-responsive polymers present great advantages in the targeted delivery and release of drugs. In this study, a novel type of thermo-responsive polymer called 2-hydroxy-3-(2-propynyloxy) propyl hydroxyethyl starch (PyHES) was synthesized via hydrophobic modification of hydroxyl groups in hydroxyethyl starch (HES) with 2- propynylglycidyl ether (PGE). Aqueous PyHES solutions with an appropriate degree of substitution (DS) of hydrophobic propynyl groups exhibited strong thermo-responsive properties as well as a cloud point temperature (Tcp) that could be tuned within a range of 31 to 48 °C by changing the DS or PyHES concentrations. Moreover, the Tcp decreased with increases in the DS or the concentration of PyHES. The Tcp of PyHES had a linear relationship with DS, and DLS characterizations indicated that PyHES can form thermo-responsive micellar nanoparticles in aqueous solutions. In addition, PyHES can be further functionalized via click reaction of the propynyl group.
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影响因子：
2.4
作者：
Phan HT;Zhu K;Kjøniksen AL;Nyström B
通讯作者：
Nyström B
DOI：
10.1080/00222348.2015.1012479
发表时间：
2015-02
期刊：
Journal of Macromolecular Science, Part B
影响因子：
--
作者：
M. Sirousazar;Y. Shaabani
通讯作者：
M. Sirousazar;Y. Shaabani
影响因子：
4.6
作者：
Y. Ohya;M. Toyohara;M. Sasakawa;Hidetoshi Arimura;T. Ouchi
通讯作者：
Y. Ohya;M. Toyohara;M. Sasakawa;Hidetoshi Arimura;T. Ouchi
影响因子：
6
作者：
Jamroz-Piegza, M.;Utrata-Wesolek, A.;Dworak, A.
通讯作者：
Dworak, A.
影响因子：
2.4
作者：
Antoniraj, M. Gover;Kumar, C. Senthil;Kandasamy, Ruckmani
通讯作者：
Kandasamy, Ruckmani