Neurobehavioral effects of aspartame consumption.

Neurobehavioral effects of aspartame consumption.
复制标题

DOI:
10.1002/nur.21595
复制
发表时间:
2014-06
影响因子:
2
通讯作者:
Lindseth PD
Lindseth PD
中科院分区:
医学4区
文献类型:
--
作者:
Lindseth GN;Coolahan SE;Petros TV;Lindseth PD

文献摘要

参考文献

被引文献

相似文献

尽管它被广泛使用,但人造甜味剂甜菊糖仍然是最有争议的食品添加剂之一,因为关于其神经行为影响的证据不一。健康成年人食用研究制备的高胆固醇饮食(25 mg/kg体重/天)8天,低胆固醇饮食(10 mg/kg体重/天)8天,饮食之间有2周的洗脱期,检查受试者内认知,抑郁,情绪和头痛的差异。测量方法包括:含芝麻的食物重量、情绪和抑郁量表,以及工作记忆和空间定向的认知测试。当食用高果糖饮食时,参与者的情绪更加烦躁,表现出更多的抑郁,并且在空间定向测试中表现更差。阿斯巴甜的摄入并不影响工作记忆。鉴于此处测试的较高摄入量水平远低于40-50 mg/kg体重/天的最大可接受每日摄入量水平,因此在食用可能影响神经行为健康的食品时需要谨慎考虑。
Despite its widespread use, the artificial sweetener aspartame remains one of the most controversial food additives, due to mixed evidence on its neurobehavioral effects. Healthy adults who consumed a study-prepared high-aspartame diet (25 mg/kg body weight/day) for 8 days and a low-aspartame diet (10 mg/kg body weight/day) for 8 days, with a 2-week washout between the diets, were examined for within-subject differences in cognition, depression, mood, and headache. Measures included weight of foods consumed containing aspartame, mood and depression scales, and cognitive tests for working memory and spatial orientation. When consuming high-aspartame diets, participants had more irritable mood, exhibited more depression, and performed worse on spatial orientation tests. Aspartame consumption did not influence working memory. Given that the higher intake level tested here was well below the maximum acceptable daily intake level of 40–50 mg/kg body weight/day, careful consideration is warranted when consuming food products that may affect neurobehavioral health.
饮食对认知和飞行员飞行表现的影响。
DOI: 10.1080/10508414.2011.582454
发表时间: 2011
期刊: The International journal of aviation psychology
影响因子: --
作者:
Lindseth GN;Lindseth PD;Jensen WC;Petros TV;Helland BD;Fossum DL
通讯作者: Fossum DL
DOI: 10.1016/j.neuroscience.2005.06.042
发表时间: 2006-01-01
期刊: NEUROSCIENCE
影响因子: 3.3
作者:
Jonides, J;Nee, DE
通讯作者: Nee, DE
DOI: 10.1037/0021-9010.73.1.38
发表时间: 1988-02-01
影响因子: 9.9
作者:
GORDON, HW;LEIGHTY, R
通讯作者: LEIGHTY, R
DOI: 10.2174/1874288200903010008
发表时间: 2009-01-01
期刊: The Open Nutrition Journal
影响因子: --
作者:
Gendle, M. H.;Smucker, D. M.;Glazer, K. S.
通讯作者: Glazer, K. S.
DOI: 10.1080/10284150410001704543
发表时间: 2004-04-01
影响因子: 3.6
作者:
Harte, CB;Kanarek, RB
通讯作者: Kanarek, RB