Sexual serosorting among women with or at risk of HIV infection.

Sexual serosorting among women with or at risk of HIV infection.
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DOI:
10.1007/s10461-010-9710-3
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发表时间:
2011-01
期刊:
影响因子:
4.4
通讯作者:
Wilson, Tracey E.
Wilson, Tracey E.
中科院分区:
医学2区
文献类型:
--
作者:
Liu, Chenglong;Hu, Haihong;Goparaju, Lakshmi;Plankey, Michael;Bacchetti, Peter;Weber, Kathleen;Correa, Nereida;Nowicki, Marek;Wilson, Tracey E.

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血清分选,选择性地与相同艾滋病毒血清状态的伴侣进行无保护性行为的做法,已被提议作为降低男男性行为者(MSM)艾滋病毒传播风险的战略。然而,关于妇女是否进行血清分选,缺乏科学证据。我们分析了2001年至2005年妇女艾滋病跨部门研究中收集的妇女与男性伴侣性行为的纵向数据。血清分选定义为血清一致性伴侣中无保护肛交或阴道性交(UAVI)随时间推移呈增加趋势,与非一致性伴侣相比,血清一致性伴侣中UAVI更频繁,或仅与血清一致性伴侣发生UAVI。重复测量泊松回归模型被用来研究艾滋病毒感染和未感染艾滋病毒的妇女血清状态伙伴关系和UAVI之间的关联。研究样本包括1 602名艾滋病毒感染者和664名未感染艾滋病毒的妇女。在随访期间,未感染艾滋病毒的妇女血清学一致的伙伴关系的频率增加,但UAVI的流行率血清学一致的伙伴关系保持稳定。艾滋病毒血清一致性伙伴关系中UAVI的报告频率高于血清不一致或血清状态未知的伙伴关系,无论参与者的艾滋病毒状态或伙伴类型。在有艾滋病毒感染和艾滋病毒未感染伴侣的妇女中,41%(63名艾滋病毒感染者和9名艾滋病毒未感染者)仅与血清一致的伴侣发生UAVI。我们的分析表明,血清分选是发生在艾滋病毒感染和艾滋病毒未感染的妇女在这个队列。
Serosorting, the practice of selectively engaging in unprotected sex with partners of the same HIV serostatus, has been proposed as a strategy for reducing HIV transmission risk among men who have sex with men (MSM). However, there is a paucity of scientific evidence regarding whether women engage in serosorting. We analyzed longitudinal data on women’s sexual behavior with male partners collected in the Women’s Interagency HIV Study from 2001 to 2005. Serosorting was defined as an increasing trend of unprotected anal or vaginal sex (UAVI) within seroconcordant partnerships over time, more frequent UAVI within seroconcordant partnerships compared to non-concordant partnerships, or having UAVI only with seroconcordant partners. Repeated measures Poisson regression models were used to examine the associations between serostatus partnerships and UAVI among HIV-infected and HIV-uninfected women. The study sample consisted of 1,602 HIV-infected and 664 HIV-uninfected women. Over the follow-up period, the frequency of seroconcordant partnerships increased for HIV-uninfected women but the prevalence of UAVI within seroconcordant partnerships remained stable. UAVI was reported more frequently within HIV seroconcordant partnerships than among serodiscordant or unknown serostatus partnerships, regardless of the participant’s HIV status or types of partners. Among women with both HIV-infected and HIV-uninfected partners, 41% (63 HIV-infected and 9 HIV-uninfected) were having UAVI only with seroconcordant partners. Our analyses suggest that serosorting is occurring among both HIV-infected and HIV-uninfected women in this cohort.
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