Agitation, aggression, and disinhibition syndromes after traumatic brain injury.

Agitation, aggression, and disinhibition syndromes after traumatic brain injury.
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创伤性脑损伤后的激越、攻击性和去抑制综合征。

DOI:
10.3233/nre-2002-17404
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发表时间:
2002
影响因子:
2
通讯作者:
Edward Kim
Edward Kim
中科院分区:
医学4区
文献类型:
--
作者:
Edward Kim

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外伤性脑损伤(TBI)常并发抑制解除和攻击。这些往往是深刻的个性变化,对康复治疗和重返社区构成障碍。症状表现可能包括冲动控制丧失、自发攻击和躁郁症。下额叶功能障碍的常见神经病理学结果支持脑外伤引起的攻击行为的解除抑制和点燃模型。评估这些高度破坏性的症状需要详细的病史、临床和神经心理学信息,以制定适当的策略。创伤性脑损伤相关攻击的管理可能涉及药物、环境和心理治疗策略,包括护理人员培训和支持。
Traumatic brain injury (TBI) is frequently complicated by disinhibition and aggression. These often profound changes in personality, present obstacles to rehabilitative treatments and community reentry. Syndromal presentations may involve a loss of impulse control, spontaneous aggression, and dysphoric bipolar states. Common neuropathological findings of inferior frontal lobe dysfunction support both disinhibition and kindling models of TBI-induced aggression. Assessment of these highly disruptive symptoms requires detailed historical, clinical, and neuropsychological information to formulate appropriate strategies. Management of TBI-related aggression may involve pharmacological, environmental, and psychotherapeutic strategies that incorporate caregiver training and support.
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