Schistosoma mansoni Infection and Its Related Morbidity among Adults Living in Selected Villages of Mara Region, North-Western Tanzania: A Cross-Sectional Exploratory Study.
Schistosoma mansoni Infection and Its Related Morbidity among Adults Living in Selected Villages of Mara Region, North-Western Tanzania: A Cross-Sectional Exploratory Study.
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DOI：
10.3347/kjp.2017.55.5.533
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发表时间：
2017-10
期刊：
影响因子：
--
通讯作者：
Kinung'hi SM
中科院分区：
文献类型：
--
作者：
Mazigo HD;Nuwaha F;Dunne DW;Kaatano GM;Angelo T;Kepha S;Kinung'hi SM
曼氏血吸虫在坦桑尼亚高度流行，对所有年龄段的人都有不同程度的影响。然而，它的控制方法不包括同样面临风险和感染的成年人。为了证明坦桑尼亚将成年人纳入MDA计划的合理性，本研究重点确定了成年人中曼氏葡萄球菌感染的流行率及其相关发病率。这是一项横断面研究，对居住在维多利亚湖沿岸罗亚和布蒂亚马地区选定村庄的412名18-年龄的成年人进行了研究。使用预先测试的问卷收集参与者的社会人口和社会经济信息。使用Niamey方案对所有研究参与者进行超声检查。从所有研究参与者身上获取一份粪便样本，并使用Kato-Katz技术检查曼氏葡萄球菌。研究表明，曼氏葡萄球菌的流行率很高(56.3%)，大多数感染者的感染强度较轻。超声检查显示22.4%的成人存在门静脉周围纤维化(C-F级)，其中18.4%为C级和D级，4%为E级和F级，男性门脉周围纤维化的患病率最高(31.7%比10.8%，P<；0.001)。器官肿大最常见，其中脾肿大占28.5%，肝肿大占29.6%。曼氏沙门氏菌感染及其相关疾病包括PPF、肝肿大和脾肿大在成人中很常见。为了减少曼氏葡萄球菌感染的传播水平，有计划的大规模药物管理活动应该包括居住在这些村庄的成年人。
Schistosoma mansoni is highly endemic in Tanzania and affects all age groups at different degrees. However, its control approach does not include adult individuals who are equally at risk and infected. To justify the inclusion of adult individuals in MDA programs in Tanzania, the present study focused on determining the prevalence of S. mansoni infection and its related morbidities among adult individuals. This was a cross sectional study conducted among 412 adult individuals aged 18–89 years living in selected villages of Rorya and Butiama districts located along the shoreline of the Lake Victoria. A pretested questionnaire was used to collect socio-demographic and socio-economic information of participants. Ultrasonographic examinations were conducted for all study participants using the Niamey protocol. A single stool sample was obtained from all study participants and examined for S. mansoni using the Kato-Katz technique. The study revealed a high prevalence of S. mansoni (56.3%), and the majority of infected individuals had a light intensity of infection. Ultrasonographic findings revealed that 22.4% of adult individuals had periportal fibrosis (PPF) (grade C–F), with 18.4% having grade C and D and 4% having grade E and F. Males had the highest prevalence of PPF (31.7% vs 10.8%, P<0.001). Organomegaly was common with 28.5% and 29.6% having splenomegaly and hepatomegaly, respectively. S. mansoni infection and its related morbidities included PPF, hepatomegaly, and splenomegaly were common among adult individuals. To reduce the level of transmission of S. mansoni infection, planned mass drug administration campaigns should include adult individuals living in these villages.
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影响因子：
3.8
作者：
Montresor A;Cong DT;Sinuon M;Tsuyuoka R;Chanthavisouk C;Strandgaard H;Velayudhan R;Capuano CM;Le Anh T;Tee Dató AS
通讯作者：
Tee Dató AS
DOI：
10.4269/ajtmh.1995.53.660
发表时间：
1995-12-01
影响因子：
3.3
作者：
Guyatt, H;Gryseels, B;Tanner, M
通讯作者：
Tanner, M
DOI：
10.1016/0035-9203(95)90498-0
发表时间：
1995-03-01
影响因子：
2.2
作者：
BOISIER, P;SERIEYE, J;ESTERRE, P
通讯作者：
ESTERRE, P
影响因子：
--
作者：
De Clercq, D;Sacko, M;Vercruysse, J
通讯作者：
Vercruysse, J
影响因子：
3.3
作者：
Gazzinelli, A;Bethony, J;Kloos, H
通讯作者：
Kloos, H