Population-Based Study of Bloodstream Infection Incidence and Mortality Rates, Finland, 2004-2018.

Population-Based Study of Bloodstream Infection Incidence and Mortality Rates, Finland, 2004-2018.
复制标题

DOI:
10.3201/eid2710.204826
复制
发表时间:
2021-10
影响因子:
11.8
通讯作者:
Lyytikäinen O
Lyytikäinen O
中科院分区:
医学2区
文献类型:
--
作者:
Kontula KSK;Skogberg K;Ollgren J;Järvinen A;Lyytikäinen O

文献摘要

参考文献

被引文献

相似文献

在此期间,发病率和死亡率增加了两倍,这说明需要作出更多的预防努力。我们使用国家登记处的数据评估了2004-2018年间芬兰血液感染(BSI)的发病率、结果和致病因素。我们总共确认了173,715例BSI;每年的发病率从150例/10万人增加到309例/10万人。BSI的发病率在80岁以上的人群中上升最快。1个月病死率从13.0%下降到12.6%,但1个月全因死亡率从每10万人口20人上升到39人。由大肠埃希菌引起的脑源性感染占所有脑源性感染的比例从26%上升到30%。多重耐药菌引起的细菌感染从0.4%上升到2.8%,主要由产超广谱β内酰胺酶的大肠埃希菌引起。我们观察到社区获得的BSI增加了,从67%增加到78%。患有严重潜在疾病的患者比例从14%上升到23%。需要更多的公共卫生和医疗保健预防努力,以遏制社区获得的细菌感染和耐药大肠杆菌的增加趋势。
A 2-fold increase in incidence and death during this period emphasizes the need for additional prevention efforts. We evaluated the incidence, outcomes, and causative agents of bloodstream infections (BSI) in Finland during 2004–2018 by using data from the national registries. We identified a total of 173,715 BSIs; annual incidence increased from 150 to 309 cases/100,000 population. BSI incidence rose most sharply among persons >80 years of age. The 1-month case-fatality rate decreased from 13.0% to 12.6%, but the 1-month all-cause mortality rate rose from 20 to 39 deaths/100,000 population. BSIs caused by Escherichia coli increased from 26% to 30% of all BSIs. BSIs caused by multidrug-resistant microbes rose from 0.4% to 2.8%, mostly caused by extended-spectrum β-lactamase-producing E. coli. We observed an increase in community-acquired BSIs, from 67% to 78%. The proportion of patients with severe underlying conditions rose from 14% to 23%. Additional public health and healthcare prevention efforts are needed to curb the increasing trend in community-acquired BSIs and antimicrobial drug–resistant E. coli.
DOI: 10.1186/1471-2334-12-85
发表时间: 2012-04-09
影响因子: 3.7
作者:
Lenz R;Leal JR;Church DL;Gregson DB;Ross T;Laupland KB
通讯作者: Laupland KB
DOI: 10.1128/aac.00355-19
发表时间: 2019-07-01
影响因子: 4.9
作者:
Diekema, Daniel J.;Hsueh, Po-Ren;Jones, Ronald N.
通讯作者: Jones, Ronald N.
DOI: 10.3109/23744235.2015.1131329
发表时间: 2016-05-03
影响因子: 5.8
作者:
Kontula, Keiju S. K.;Skogberg, Kirsi;Lyytikainen, Outi
通讯作者: Lyytikainen, Outi
DOI: 10.1111/j.1469-0691.2012.03845.x
发表时间: 2012-06-01
影响因子: 14.2
作者:
Skogberg, K.;Lyytikainen, O.;Ruutu, P.
通讯作者: Ruutu, P.
DOI: 10.1001/archinte.167.8.834
发表时间: 2007-04-23
影响因子: --
作者:
Uslan, Daniel Z.;Crane, Sarah J.;Baddour, Larry M.
通讯作者: Baddour, Larry M.