What are the clinical signs of thiamine deficiency in elderly patients?
What are the clinical signs of thiamine deficiency in elderly patients?
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DOI：
10.1002/jgf2.479
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发表时间：
2022-01
影响因子：
1.6
通讯作者：
Ishida M
中科院分区：
文献类型：
--
作者：
Onishi H;Ishida M
致编辑，我们怀着极大的兴趣阅读了太田等人的论文。1这篇论文似乎是重要的，因为它检查的频率和相关因素的维生素B1缺乏症在综合医院通过详细的研究，临床实践的医生进行，从而澄清与食欲不振的关系。然而，在这篇论文中，患者的选择标准非常模糊：“存在提示维生素B1缺乏的初步发现，由普通或内科医生在入院当天根据医生的图表进行评估。”由于没有提供选择标准，因此怀疑硫胺素缺乏症的症状尚不清楚。我们在癌症医院经历了一些硫胺素缺乏症的病例。2-4许多韦尼克脑病患者也接受了检查，但没有一个表现出典型的三联征症状，如意识障碍、眼球震颤和小脑共济失调。4.我们也遇到过没有任何三联征症状和没有食欲不振的患者。2，3鉴于先前的研究5表明硫胺素缺乏症的症状是非特异性的，在本研究中，临床医生提供导致他们检查硫胺素缺乏症的症状的细节将更有用。
To the Editor, We read the paper by Ohta et al. with great interest. 1 This paper appears to be significant in that it examines the frequency of and factors related to vitamin B1 deficiency in general hospitals though a detailed study of the clinical practice undertaken by physicians, thereby clarifying the relationship with the loss of appetite. However, in this paper, the patient selection criteria are very vague:“the presence of initial findings suggestive of vitamin B1 deficiency, assessed by general or internal medicine physicians on the day of admission based on physicians’ charts.” As no selection criteria are provided, the symptoms upon which the suspicion of thiamine deficiency is based are unclear.We have experienced a number of cases of thiamine deficiency in cancer hospitals. 2–4 Many patients with Wernicke's encephalopathy have also been examined, but none have demonstrated classic triad symptoms such as impaired consciousness, nystagmus, and cerebellar ataxia. 4 We have also experienced patients who do not have any of the triad of symptoms and those who do not have a loss of appetite. 2, 3 Given that previous study5 has shown that the symptoms of thiamine deficiency are nonspecific, it would be more useful for clinicians to provide details of the symptoms that led them to an examination of thiamine deficiency in this study.
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影响因子：
2.2
作者：
Onishi, Hideki;Uchida, Nozomu;Ishida, Mayumi
通讯作者：
Ishida, Mayumi
怀疑缺乏症的老年患者的瞬时食欲丧失与维生素B1缺乏症之间的关联。
影响因子：
1.6
作者：
Ohta R;Ryu Y;Hattori S
通讯作者：
Hattori S
影响因子：
4.7
作者：
Onishi H;Sato I;Uchida N;Takahashi T;Furuya D;Ebihara Y;Yoshioka A;Ito H;Ishida M
通讯作者：
Ishida M
影响因子：
2.2
作者：
Onishi, Hideki;Ishida, Mayumi;Akechi, Tatsuo
通讯作者：
Akechi, Tatsuo