Association between transient appetite loss and vitamin B1 deficiency in elderly patients with suspected deficiency.
Association between transient appetite loss and vitamin B1 deficiency in elderly patients with suspected deficiency.
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怀疑缺乏症的老年患者的瞬时食欲丧失与维生素B1缺乏症之间的关联。
DOI：
10.1002/jgf2.404
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发表时间：
2021-05
影响因子：
1.6
通讯作者：
Hattori S
中科院分区：
文献类型：
--
作者：
Ohta R;Ryu Y;Hattori S
缺乏证据表明，维生素B1水平和食欲不振持续时间在老年患者怀疑B1缺乏症。我们的目的是调查这种关联在老年住院患者怀疑在日本农村维生素B1缺乏症。这项横断面研究评估了2017年4月至2019年3月期间在一家农村医院住院的309例老年患者（年龄≥ 65岁）。我们从患者的电子病历中收集了维生素B1水平、年龄、性别、体重指数、白蛋白水平、居住地区、长期护理、依赖条件、日常生活活动、Charlson合并症指数和食欲不振的数据。维生素B1缺乏定义为血清维生素B1水平<20 μg/dL。使用Mann-Whitney U，Student t和卡方检验分析数据，然后进行多变量logistic回归，以检查维生素B1缺乏和食欲不振之间的关联。88例（28.5%）患者患有维生素B1缺乏症。在多变量logistic回归分析中，入院前食欲不振（均为< 1 and >1周）与维生素B1缺乏显著相关（校正比值比[AOR] =10.80，95%置信区间[CI]：5.16 - 22.00，P <0.001; AOR = 5.77，95% CI：2.88 - 11.50，P <0.001）。食欲减退与生活在农村地区的日本老年患者的维生素B1缺乏有关。因此，医生应意识到老年食欲减退患者维生素B1缺乏的可能性，并注重早期干预。这项研究阐明了日本农村老年患者短期食欲不振与维生素B1缺乏之间的正相关性
There is scarce evidence associating vitamin B1 levels and appetite loss duration in elderly patients with suspected B1 deficiency. We aimed to investigate this association in elderly hospitalized patients with suspected vitamin B1 deficiency in rural Japan. This cross‐sectional study evaluated 309 elderly patients (aged ≥ 65 years) admitted to one rural Hospital between April 2017 and March 2019. We collected data on vitamin B1 level, age, sex, body mass index, albumin levels, area of residence, long‐term care, dependent conditions, activities of daily living, Charlson comorbidity index, and appetite loss from the patients' electronic medical records. Vitamin B1 deficiency was defined as serum vitamin B1 levels <20 μg/dL. Data were analyzed using the Mann‐Whitney U, Student's t, and chi‐square tests, followed by multivariable logistic regression, to examine the association between vitamin B1 deficiency and appetite loss. Eighty‐eight (28.5%) patients had vitamin B1 deficiency. In multivariable logistic regression, appetite loss (for both < 1 and > 1 week) before admission to the hospital showed a significant association with vitamin B1 deficiency (adjusted odds ratio [AOR] =10.80, 95% confidence interval [CI]: 5.16‐22.00, P < .001; and AOR = 5.77, 95% CI: 2.88‐11.50, P < .001, respectively). Appetite loss is associated with vitamin B1 deficiency in elderly Japanese patients living in rural areas. Therefore, physicians should be aware of the possibility of vitamin B1 deficiency in elderly patients with appetite loss and focus on early intervention. This study clarifies the positive association between the short duration of appetite loss and vitamin B1 deficiency among older patients in rural Japan
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影响因子：
3.1
作者：
Moore, L.;Deehan, A.;Jones, R.
通讯作者：
Jones, R.
影响因子：
4.6
作者：
Ahmed, Mavra;Azizi-Namini, Parastoo;Keith, Mary
通讯作者：
Keith, Mary
影响因子：
1.9
作者：
Blitshteyn, Svetlana
通讯作者：
Blitshteyn, Svetlana
影响因子：
1.9
作者：
Muthayya, Sumithra;Hall, Jessica;Maberly, Glen
通讯作者：
Maberly, Glen
影响因子：
19.6
作者：
DESCOMBES, E;HANCK, AB;FELLAY, G
通讯作者：
FELLAY, G